9-HYDRAZINOACRIDINE

The Acridine, 9-hydrazinyl-, with the CAS registry number of 3407-93-0, is also known as 9-Hydrazinoacridine and p-Hydrazinoacridine. This chemical's molecular formula is C₁₃H₁₁N₃ and molecular weight is 209.25. What's more, its IUPAC name is Acridin-9-ylhydrazine. This chemical's classification code is Drug / Therapeutic Agent. In addition, it must be stored in airtight containers and placed in a dry, cool place at -20 °C. Meanwhile, it should avoid contact with oxidant, moisture, incompatible material.

Physical properties about Acridine, 9-hydrazinyl- are: (1)ACD/LogP: 2.43; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.04; (4)ACD/LogD (pH 7.4): 1.29; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 2.96; (7)ACD/KOC (pH 5.5): 2.05; (8)ACD/KOC (pH 7.4): 35.79; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 19.37 Å²; (13)Index of Refraction: 1.819; (14)Molar Refractivity: 68.54 cm³; (15)Molar Volume: 157.5 cm³; (16)Surface Tension: 70.9 dyne/cm; (17)Density: 1.328 g/cm³; (18)Flash Point: 241.6 °C; (19)Enthalpy of Vaporization: 73.95 kJ/mol; (20)Boiling Point: 475.9 °C at 760 mmHg; (21)Vapour Pressure: 3.19E-09 mmHg at 25 °C.

Preparation: this chemical is prepared by heating 9-Chloroacridine with Hydrazine in the presence of Platinum and small amounts of alkali.

Uses: it is used as synthetic organic intermediate to produce other chemicals. For example, it is used to produce 9-Benzal hydrazinoacridine. This reaction needs solvent Methanol. The reaction time is 3 hours with reaction temperature of 70-80 °C. The yield is about 65 %.

 

When you are using this chemical, please be cautious about it as the following:
As a chemical, it is toxic by inhalation and in contact with skin. In addition, this chemical is very toxic if swallowed. During using it, wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1) SMILES: n1c3c(c(c2c1cccc2)NN)cccc3
(2) InChI: InChI=1/C13H11N3/c14-16-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H,14H2,(H,15,16)
(3) InChIKey: SVANEUDZNISLJD-UHFFFAOYAH

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LD50	unreported	12mg/kg (12mg/kg)		Farmatsevtichnii Zhurnal Vol. (4), Pg. 40, 1984.