-
Name
Choline salicylate
- EINECS 217-948-8
- CAS No. 2016-36-6
- Article Data11
- CAS DataBase
- Density g/cm3
- Solubility
- Melting Point 49.5-50.0°
- Formula C7H5O3.C5H14NO
- Boiling Point 336.3 °C at 760 mmHg
- Molecular Weight 241.287
- Flash Point 144.5 °C
- Transport Information
- Appearance Clear, colourless liquid
- Safety Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. An analgesic and antipyretic. When heated to decomposition it emits toxic fumes of NOx and NH3. See also CHOLINE.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms (2-Hydroxyethyl)trimethylammonium salicylate
- PSA 80.59000
- LogP -0.55940
Synthetic route
| Conditions | Yield |
|---|---|
| In methanol at 20℃; for 12h; | 100% |
| at 20 - 50℃; for 2h; | 98% |
| With OH- | 98% |
| In ethanol; water at 25℃; | |
| In water at 20℃; for 12h; |
| Conditions | Yield |
|---|---|
| In acetone for 72h; | 100% |
| In ethanol at 20℃; for 1h; |
| Conditions | Yield |
|---|---|
| In acetone |
Choline Salicylate Chemical Properties
Chemistry informtion about Choline Salicylate (CAS NO.2016-36-6) is:
IUPAC Name: 2-Hydroxybenzoate; 2-Hydroxyethyl(Trimethyl)Azanium
Synonyms: (2-Hydroxyethyl)Trimethylammoniumsalicylate ; 2-Hydroxy-N,N,N-Trimethylethanaminiumsaltwith2-Hydroxybenzoicacid(1:1) ; 2-Hydroxy-N,N,N-Trimethyl-Ethanaminiusaltwith2-Hydroxybenzoicacid(1: ; 2-Hydroxy-N,N,N-Trimethyl-Ethanaminiusaltwith2-Hydroxybenzoicacid(1:1) ; Actasal ; Arret ; Arthropan ; Artrobione
MF: C12H19NO4
MW: 241.28
EINECS: 217-948-8
Flash Point: 144.5 °C
Boiling Point: 336.3 °C at 760 mmHg
Vapour Pressure: 4.45E-05 mmHg at 25°C
Enthalpy of Vaporization: 61.16 kJ/mol
Following is the molecular structure of Choline Salicylate (CAS NO.2016-36-6) is:
Choline Salicylate Uses
Choline Salicylate (CAS NO.2016-36-6) was used for temporary relief of pain of rheumatoid arthritis, rheumatic fever, osteoarthritis, and other conditions for which oral salicylates are recommended; useful in patients in which there is difficulty in administering doses in a tablet or capsule dosage form, because of the liquid dosage form.
Choline Salicylate Toxicity Data With Reference
| 1. | orl-mus LD50:2690 | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),291. | ||
| 2. | ipr-mus LD50:410 mg/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),291. | ||
| 3. | scu-mus LD50:1 g/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),291. |
Choline Salicylate Consensus Reports
Reported in EPA TSCA Inventory.
Choline Salicylate Safety Profile
Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. An analgesic and antipyretic. When heated to decomposition it emits toxic fumes of NOx and NH3. See also CHOLINE.
Safty information about Choline Salicylate (CAS NO.2016-36-6) :
WGK Germany: 2
RTECS: GA6475000
F:
F 3: Hygroscopic.
F 10 Keep under argon.
Related Products
- Choline
- Choline (1alpha,3alpha,4alpha,5beta)-1,3-bis(3,4-dihydroxycinnamoyloxy)-4,5-dihydroxycyclohexanecarboxylate
- Choline acetate (ester)
- Choline bicarbonate
- Choline bitartrate
- Choline chloride
- Choline dihydrogencitrate salt
- Choline fenofibrate
- Choline glycerophosphate
- Choline hydroxide
- 2016-42-4
- 2016-52-6
- 2016-56-0
- 2016-57-1
- 201660-37-9
- 2016-63-9
- 20166-49-8
- 201668-30-6
- 201-67-2
- 201677-20-5
Hot Products
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View