D-Cycloserine

The Cycloserine, with the CAS registry number 68-41-7 and EINECS registry number 200-688-4, has the systematic name of (4R)-4-amino-1,2-oxazolidin-3-one. It is a kind of white to pale crystal powder, and belongs to the following product categories: Variousamine; Miscellaneous Biochemicals; Chiral; Amines (Chiral); Chiral Building Blocks; Synthetic Organic Chemistry; Amino Acids; Glutamate receptor; Glutamate; Antibiotics. And the molecular formula of this chemical is C₃H₆N₂O₂. What's more, it should be stored at -20°C.

The physical properties of Cycloserine are as followings: (1)ACD/LogP: -2.988; (2)ACD/LogD (pH 5.5): -3.54; (3)ACD/LogD (pH 7.4): -3.00; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 1.00; (7)ACD/KOC (pH 7.4): 1.00; (8)#H bond acceptors: 4; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 1; (11)Index of Refraction: 1.475; (12)Molar Refractivity: 22.472 cm³; (13)Molar Volume: 79.861 cm³; (14)Polarizability: 8.909 10-24cm³; (15)Surface Tension: 40.8849983215332 dyne/cm; (16)Density: 1.278 g/cm³

Preparation of Cycloserine: It can be synthesised by fomentation and direct synthesis technique. Fomentation need zymogen the Actinomyces laven-dulae, and the fermentation medium dextrin, glucose, starch, soybean powder, yeast powder, ammonium sulfate, ammonium nitrate, calcium carbonate, sodium chloride, magnesium sulfate, soybean oil and so on. Direct synthesis technique is a cyclization reaction between β-amino alanine ethyl ester dihydrochloride oxygen and KOH.

Uses of Cycloserine: It is an antibiotic effective against Mycobacterium tuberculosis, and usually used for the treatment of tuberculosis. It is also being trialed as an adjuvant to exposure therapy for anxiety disorders. 

You should be cautious while dealing with this chemical. Heating may cause an explosion, and it is also harmful by inhalation. Therefore, you had better take the following instructions: Wear suitable protective clothing, gloves and eye/face protection, and avoid contacting with skin and eyes.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C1NOC[C@H]1N
(2)InChI: InChI=1/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
(3)InChIKey: DYDCUQKUCUHJBH-UWTATZPHBN

The toxicity data is as follows: