• Name

  Ethyl 6,8-dichloro caprylate

• EINECS 435-080-1
• CAS No. 41443-60-1
• Article Data3
• CAS DataBase
• Density 1.107 g/mL
• Solubility
• Melting Point
• Formula C8H14 Cl2 O2
• Boiling Point 288.5ºC at 760 mmHg
• Molecular Weight 213.104
• Flash Point >230 °F
• Transport Information
• Appearance Colorless to yellowish transparent liquid
• Safety 26-36
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms 6,8-Dichlorooctanoicacid
• PSA 26.30000
• LogP 3.34620

Synthetic route

90435-60-2

(+)-8-chloro-6-hydroxy-octanoic acid

41443-60-1

(+)-6,8-dichloro-octanoic acid

Conditions

Conditions	Yield
With pyridine; sodium hydroxide; thionyl chloride In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; toluene	80%

(+-)-6,8-dichloro-octanoic acid ethyl ester

(+-)-6,8-dichloro-octanoic acid ethyl ester

41443-60-1

(+)-6,8-dichloro-octanoic acid

Conditions

Conditions	Yield
With hydrogenchloride

(-)-6,8-dichlorooctanoic acid

41443-60-1

(+)-6,8-dichloro-octanoic acid

Conditions

Conditions	Yield
Stage #1: (-)-6,8-dichlorooctanoic acid With sodium hydroxide In 2-methoxy-ethanol; water at 60℃; for 5h; Stage #2: With sulfuric acid In 2-methoxy-ethanol; water pH=1 - 2;

1070-64-0

6,8-dichlorooctanoic acid ethyl ester

41443-60-1

(+)-6,8-dichloro-octanoic acid

Conditions

Conditions	Yield
Alkaline aqueous solution;

41443-60-1

(+)-6,8-dichloro-octanoic acid

2627-86-3

(S)-1-phenyl-ethylamine

3886-69-9

(R)-1-phenyl-ethyl-amine

A

(R)-(+)-6,8-dichlorooctanoic acid S(-)α-methylbenzylamine salt

B

(S)-(-)-6,8-dichlorooctanoic acid R(+)α-methylbenzylamine salt

Conditions

Conditions	Yield
Stage #1: (+)-6,8-dichloro-octanoic acid; (S)-1-phenyl-ethylamine In ethyl acetate at 0 - 20℃; Resolution of racemate; Stage #2: (R)-1-phenyl-ethyl-amine In ethyl acetate at 0 - 20℃; Resolution of racemate;	A 45% B n/a

...Expand

41443-60-1

(+)-6,8-dichloro-octanoic acid

41443-60-1, 98441-83-9

6,8-dichloro-octanoic acid

Conditions

Conditions	Yield
With ephedrine dextrorotatory form;
With ephedrine levorotatory form;

41443-60-1

(+)-6,8-dichloro-octanoic acid

462-20-4, 7516-48-5, 98441-85-1, 119365-69-4

(-)-Dihydrolipoic acid

Conditions

Conditions	Yield
Multistep reaction;

41443-60-1

(+)-6,8-dichloro-octanoic acid

2627-86-3

(S)-1-phenyl-ethylamine

(+)-6,8-dichlorooctanoic acid-(S)-(-)-α-methylbenzylamine

Conditions

Conditions	Yield
In ethyl acetate at 0 - 10℃;
Stage #1: (+)-6,8-dichloro-octanoic acid; (S)-1-phenyl-ethylamine In ethyl acetate at 18 - 20℃; Stage #2: In ethyl acetate at 0 - 5℃;

41443-60-1

(+)-6,8-dichloro-octanoic acid

3886-69-9

(R)-1-phenyl-ethyl-amine

(-)-6,8-dichlorooctanoic acid-(R)-(+)-methylbenzylamine

41443-60-1

(+)-6,8-dichloro-octanoic acid

C8H14O8S4(2-)*2Na(1+)

Conditions

Conditions	Yield
With sodium thiosulfate In ethanol; water at 60 - 70℃; for 6h;

Ethyl 6,8-dichloro caprylate Chemical Properties

Molecular Formula: C₁₀H₁₈Cl₂O₂ 
Molar mass: 241.1547 g/mol
Density: 1.094 g/cm³
Flash Point: 105.1 °C
Index of Refraction: 1.455
Boiling Point: 288.5 °C at 760 mmHg
Vapour Pressure: 0.00233 mmHg at 25°C
Structure of Ethyl 6,8-dichloro caprylate(41443-60-1):
                
Synonyms of Ethyl 6,8-dichloro caprylate(41443-60-1): 6,8-Dichloro Ethyl Caprylate;6,8-Dichloro-octanoic acid ethyl ester;6,8-Dichloro-octanoic acid ethyl ester;6,8-DICHLOROCAPRYLATE
Product Categoriy of Ethyl 6,8-dichloro caprylate(41443-60-1): Ester series;Organic acids

Ethyl 6,8-dichloro caprylate Safety Profile

Hazard Codes:Xi
Risk Statements:
36:  Irritating to the eyes
37:  Irritating to the respiratory system
38:  Irritating to the skin
Safety Statements:
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing