Methyl 3-methoxythiophene-2-carboxylate

The Methyl 3-methoxythiophene-2-carboxylate, with the CAS registry number 62353-75-7, is also known as 3-Methoxythiophene-2-carboxylicacid methyl ester. It belongs to the product categories of Esters; Thiophenes & Benzothiophenes; Thiophenes & Benzothiophenes. This chemical's molecular formula is C₇H₈O₃S and molecular weight is 172.2. What's more, its IUPAC name is Methyl 3-methoxythiophene-2-carboxylate. In addition, it must be stored in airtight containers and placed in a dry, cool place. Meanwhile, it should be kept away from oxidant.

Physical properties about Methyl 3-methoxythiophene-2-carboxylate are: (1)ACD/LogP: 1.64; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 3; (4)#H bond donors: 0; (5)#Freely Rotating Bonds: 3; (6)Polar Surface Area: 63.77 Å²; (7)Index of Refraction: 1.524; (8)Molar Refractivity: 43.08 cm³; (9)Molar Volume: 140.8 cm³; (10)Polarizability: 17.08×10^-24 cm³; (11)Surface Tension: 39 dyne/cm; (12)Density: 1.222 g/cm³; (13)Flash Point: 108.2 °C; (14)Enthalpy of Vaporization: 49.28 kJ/mol; (15)Boiling Point: 255.3 °C at 760 mmHg; (16)Vapour Pressure: 0.0164 mmHg at 25 °C.

Preparation of Methyl 3-methoxythiophene-2-carboxylate: this chemical is prepared by reaction of 3-Hydroxy-thiophene-2-carboxylic acid methyl ester with Sulfuric acid dimethyl ester. The reaction needs reagent aq. NaOH, catalyst +Cl-, and solvent CH₂Cl₂. The yield is about 91 %.

Uses of Methyl 3-methoxythiophene-2-carboxylate: it is used to produce other chemicals. For example, it is used to produce 3-Methoxy-thiophene-2-carboxylic acid by heating. The reaction needs reagent NaOH. The yield is about 96 %.

When you are using this chemical, please be cautious about it as the following:
As a chemical, it is irritating to eyes, respiratory system and skin. During using it, wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(OC)c1sccc1OC
(2) InChI: InChI=1/C7H8O3S/c1-9-5-3-4-11-6(5)7(8)10-2/h3-4H,1-2H3
(3) InChIKey: MWADWXJPBMFRGL-UHFFFAOYAL