N,N-Dimethylformamide dipropyl acetal supplier

Name
N,N-Dimethylformamide dipropyl acetal
EINECS 227-855-4
CAS No. 6006-65-1
Density 0.887 g/cm³
Solubility It hydrolyzes with water.
Melting Point
Formula C₉H₂₁NO₂
Boiling Point 175.9 °C at 760 mmHg
Molecular Weight 175.271
Flash Point 37.8 °C
Transport Information UN 1993
Appearance Colorless liquid.
Safety 26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Trimethylamine,1,1-dipropoxy- (7CI,8CI);DMF dipropyl acetal;Dimethylformamide dipropylacetal;N,N-Dimethylformamide dipropyl acetal;Propyl 8;
PSA 21.70000
LogP 1.68480

Synthetic route

: 71-23-8
propan-1-ol

: 3724-43-4, 149409-22-3
Vilsmeier reagent

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

Conditions

Conditions	Yield
With sodium n-propoxide In chloroform

: 25818-74-0
1,1-dichloromethyl-N,N-dimethylamine

: 6819-41-6
sodium n-propoxide

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

Conditions

Conditions	Yield
In propan-1-ol

: 2214-82-6
Bis(dimethylamino)acetonitrile

: 6819-41-6
sodium n-propoxide

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

Conditions

Conditions	Yield
In propan-1-ol

: 71-23-8
propan-1-ol

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 71-30-7
Cytosine

: 79044-11-4
N4-<(Dimethylamino)methylene>-1-propylcytosine

Conditions

Conditions	Yield
In N,N-dimethyl-formamide for 24h; Heating;	99%

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 71-30-7
Cytosine

: 76299-81-5
N4-<(Dimethylamino)methylene>cytosine

Conditions

Conditions	Yield
With trifluoroacetic acid at 85 - 90℃; for 12h;	98%

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 325733-95-7
2-amino-3-cyano-6-nitroindole

: 1383659-86-6
N'-(3-cyano-6-nitro-1-propyl-1H-indol-2-yl)-N,N-dimethylformimidamide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 120℃; under 760.051 Torr; for 0.5h; Microwave irradiation;	72%

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 2-amino-1H-indole-3-carbonitrile

: 1383659-80-0
N'-(3-cyano-1-propyl-1H-indol-2-yl)-N,N-dimethylformimidamide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 120℃; under 760.051 Torr; for 0.5h; Microwave irradiation;	69%

: 71-23-8
propan-1-ol

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 4774-33-8
tris(formylamino)methane

: 97945-47-6
N'-Dipropoxymethyl-N,N-dimethyl-formamidine

Conditions

Conditions	Yield
for 1h; Heating;	55%

...Expand

: 1-[2-(4-cyanophenyl)-2-oxo-ethyl]-2-methyl-pyridinium bromide

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

A: 4-(indolizin-2-yl)benzonitrile

B: 501948-42-1
3-(4-cyanobenzoyl) indolizine

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 130 - 135℃;	A n/a B 47%

...Expand

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 3-(2-aminoethyl)-1H-indole-5-yl-N-methyl methane sulphonamide

A 3-[2-(N,N-dipropyaminomethyleneamino)ethyl]-1H-indole-5-yl-N-methyl methanesulphonamide: 3-[2-(N,N-dipropyaminomethyleneamino)ethyl]-1H-indole-5-yl-N-methyl methanesulphonamide

B: 3-[2-(N,N-dipropylaminomethyleneamino)ethyl]-1H-indole-5-yl-N-methyl methane sulphonamide

...Expand

: 350-03-8
methyl-3-pyridylketone

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 55314-16-4, 75415-01-9, 123367-26-0
(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 540-61-4
2-aminoacetonitrile

: 114068-06-3
C8H14N4

Conditions

Conditions	Yield
at 150℃; for 48h;

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: C13H18N6O5

A: 6-N-(dimethylformamidine)-N7-methyl-8-oxoadenosine

B: 6-N-(dimethylformamidine)-N7-propyl-8-oxoadenosine

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 60℃;	A n/a B 0.26 g

...Expand

: 6006-65-1
N,N-dimethylformamide dipropyl acetal

: 5584-18-9
6-aminopyridine-2-carbohydrazide

: 1448427-99-3
6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-amine

Conditions

Conditions	Yield
With acetic acid; isopropylamine In toluene at 20 - 95℃; for 20h;

N,N-Dimethylformamide dipropyl acetal Specification

The cas register number of N,N-Dimethylformamide dipropyl acetal is 6006-65-1. It also can be called as 1-Methyl-1H-1,2,3-triazole and the Systematic name about this chemical is 1,1-Dipropoxy-N,N-dimethylmethylamine.

Physical properties about N,N-Dimethylformamide dipropyl acetal are: (1)ACD/LogP: 2.87; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.68; (4)ACD/LogD (pH 7.4): 2.87; (5)ACD/BCF (pH 5.5): 57.37; (6)ACD/BCF (pH 7.4): 89.07; (7)ACD/KOC (pH 5.5): 556.27; (8)ACD/KOC (pH 7.4): 863.72; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 7; (12)Polar Surface Area: 21.7Å²; (13)Index of Refraction: 1.429; (14)Molar Refractivity: 50.91 cm³; (15)Molar Volume: 197.4 cm³; (16)Surface Tension: 27.6 dyne/cm; (17)Density: 0.887 g/cm³; (18)Flash Point: 37.8 °C; (19)Enthalpy of Vaporization: 41.22 kJ/mol; (20)Boiling Point: 175.9 °C at 760 mmHg; (21)Vapour Pressure: 1.12 mmHg at 25°C.

Uses of N,N-Dimethylformamide dipropyl acetal: It reacts with 4-amino-1H-pyrimidin-2-one to get N4-[(Dimethylamino)methylene]-1-propylcytosine. This reaction needs solvent dimethylformamide. The reaction time is 24 hours. The yield is 99 %.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. People must wear suitable protective clothing.

People can use the following data to convert to the molecule structure.
1.SMILES: O(CCC)C(OCCC)N(C)C
2.InChI: InChI=1/C9H21NO2/c1-5-7-11-9(10(3)4)12-8-6-2/h9H,5-8H2,1-4H3
3.InChIKey: NSLGQFIDCADTAS-UHFFFAOYAP
4.Std. InChI: InChI=1S/C9H21NO2/c1-5-7-11-9(10(3)4)12-8-6-2/h9H,5-8H2,1-4H3

Product Name

N,N-Dimethylformamide dipropyl acetal

Synthetic route

N,N-Dimethylformamide dipropyl acetal Specification

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