Product Name

  • Name

    AMIPHOS

  • EINECS
  • CAS No. 13265-60-6
  • Article Data4
  • CAS DataBase
  • Density 1.265g/cm3
  • Solubility
  • Melting Point
  • Formula C6H14 N O3 P S2
  • Boiling Point °Cat760mmHg
  • Molecular Weight 243.288
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, skin contact, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. When heated to decomposition it emits very toxic NOx, POx, and SOx. See also MERCAPTANS.
  • Risk Codes
  • Molecular Structure Molecular Structure of 13265-60-6 (AMIPHOS)
  • Hazard Symbols
  • Synonyms Phosphorodithioicacid, O,O-dimethyl ester, S-ester with N-(2-mercaptoethyl)acetamide (7CI,8CI);Aminphos; Amiphos; CP 49674; DAEP; Monsanto CP 49674; O,O-DimethylS-(2-acetamidoethyl) dithiophosphate; O,O-Dimethyl S-acetylaminoethyldithiophosphate; O,O-Dimethyl-S-2-(acetylaminoethyl)dithiophosphate
  • PSA 118.25000
  • LogP 2.86390

O,O-Dimethyl-S-(2-(acetylamino)ethyl)-dithiophosphate Chemical Properties

IUPAC Name: N-(2-Dimethoxyphosphinothioylsulfanylethyl)acetamide
Synonyms of O,O-Dimethyl-S-(2-(acetylamino)ethyl)-dithiophosphate (CAS NO.13265-60-6): N-((O,O-Dimethylphosphorodithioyl)ethyl)acetamide ; O,O-Dimethyl S-(2-acetylaminoethyl) dithiophosphate ; O,O-Dimethyl S-(2-acetylaminoethyl) phosphorodithioate ; O,O-Dimethyl-S-(2-acetylaminoethyl)dithiophosphate ; Phosphorodithioic acid, O,O-dimethyl ester, S-ester with N-(2-mercaptoethylacetamide ; Phosphorodithioic acid, S-(2-(acetylamino)ethyl) O,O-dimethyl ester ; S-(2-(Acetylamino)ethyl) O,O-dimethyl phosphorodithioate
InChI: InChI=1/C6H14NO3PS2/c1-6(8)7-4-5-13-11(12,9-2)10-3/h4-5H2,1-3H3,(H,7,8)
InChIKey: BETVNUCOOCCCIO-UHFFFAOYAD
Std. InChI: InChI=1S/C6H14NO3PS2/c1-6(8)7-4-5-13-11(12,9-2)10-3/h4-5H2,1-3H3,(H,7,8)
Std. InChIKey: BETVNUCOOCCCIO-UHFFFAOYSA-N
CAS NO: 13265-60-6
Molecular Formula: C6H14NO3PS2
Molecular Weight: 243.284
Molecular Structure :
H bond acceptors: 4
H bond donors: 1
Freely Rotating Bonds: 6
Polar Surface Area: 105.97 Å2
Index of Refraction: 1.526
Molar Refractivity: 59.09 cm3
Molar Volume: 192.2 cm3
Surface Tension: 48.5 dyne/cm
Density: 1.265 g/cm3

O,O-Dimethyl-S-(2-(acetylamino)ethyl)-dithiophosphate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 410mg/kg (410mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 55, 1982.
chicken LDLo oral 45mg/kg (45mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Byulleten Vsesoiuznogo Ordena Lenina Instituta Eksperimentalnoi Veterinarii. Vol. 27, Pg. 13, 1976.
guinea pig LD50 subcutaneous 400mg/kg (400mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 57, 1967.
mammal (species unspecified) LD50 unreported 200mg/kg (200mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 375, 1971.
monkey LD50 skin 400mg/kg (400mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 57, 1967.
mouse LD50 intraperitoneal 117mg/kg (117mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 57, 1967.
mouse LD50 oral 146mg/kg (146mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 55, 1982.
mouse LD50 skin 472mg/kg (472mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS		 Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 57, 1967.
mouse LD50 subcutaneous 245mg/kg (245mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 57, 1967.
rabbit LD50 subcutaneous 400mg/kg (400mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS		 Oyo Yakuri. Pharmacometrics. Vol. 1, Pg. 57, 1967.
rat LCLo inhalation 40mg/m3/4H (40mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 55, 1982.
rat LD50 oral 220mg/kg (220mg/kg)   Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 16, 1966.
rat LD50 skin 375mg/kg (375mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 55, 1982.

O,O-Dimethyl-S-(2-(acetylamino)ethyl)-dithiophosphate Safety Profile

Poison by ingestion, skin contact, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. When O,O-Dimethyl-S-(2-(acetylamino)ethyl)-dithiophosphate (CAS NO.13265-60-6) is heated to decomposition, it emits very toxic NOx, POx, and SOx. See also MERCAPTANS.

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