Conditions | Yield |
---|---|
With water In acetonitrile at 20℃; for 1h; |
3',6'-bis(diethylamino)-2-(2-hydroxyethylamino)spiro[iso-indoline-1,9'-xanthen]-3-one
rhodamine B
Conditions | Yield |
---|---|
With Cu+ |
rhodamine B hydrazide
rhodamine B
Conditions | Yield |
---|---|
With mercury (II) perchlorate trihydrate; water In ethanol at 20℃; pH=7.0; |
rhodamine B hydrazide
rhodamine B
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: methanol / 12 h / 65 °C / Inert atmosphere 2: mercury (II) perchlorate trihydrate / ethanol; water / 20 °C / pH 7.0 3: water; mercury (II) perchlorate trihydrate / ethanol / 20 °C / pH 7.0 View Scheme | |
Multi-step reaction with 2 steps 1: ethanol / 6 h / Reflux 2: mercuric(II) nitrate monohydrate / ethanol / 0.08 h View Scheme |
Conditions | Yield |
---|---|
With trichlorophosphate In 1,2-dichloro-ethane for 2h; Reflux; |
Conditions | Yield |
---|---|
With water; hypochlorite In acetonitrile at 25℃; |
rhodamine B
Conditions | Yield |
---|---|
With mercuric(II) nitrate monohydrate In ethanol for 0.0833333h; Mechanism; |
Conditions | Yield |
---|---|
Stage #1: phthalic anhydride; 3-diethylaminophenol In 1,2-dichloro-benzene at 175℃; for 13h; Stage #2: With water; sodium hydroxide at 25℃; for 0.5h; Stage #3: With hydrogenchloride; sodium chloride In water at 80℃; for 1h; | 35 g |
With sulfuric acid at 150℃; for 2h; |
rhodamine B
Conditions | Yield |
---|---|
With copper(II) ion In water; acetonitrile Reagent/catalyst; |
Conditions | Yield |
---|---|
With trichlorophosphate In 1,2-dichloro-ethane for 3h; Reflux; |
rhodamine B hydrazide
A
N-(Rhodamine-B) lactam-hydrazine
B
rhodamine B
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: ethanol / 12 h / Reflux 2.1: potassium carbonate; potassium iodide / acetonitrile / 0.5 h 2.2: 8 h / Reflux 3.1: gold(III) chloride; water / acetonitrile / pH 7.4 View Scheme |
Conditions | Yield |
---|---|
With gold(III) chloride; water In acetonitrile pH=7.4; |
rhodamine B
Conditions | Yield |
---|---|
With hypochlorite |
2-azidoethanol
rhodamine B
N-(9-(2-((2-azidoethoxy)carbonyl)phenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethylethaniminium chloride
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 20℃; for 4h; Inert atmosphere; Darkness; | 100% |
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 24h; | 61% |
Stage #1: 2-azidoethanol; rhodamine B With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 4h; Inert atmosphere; Darkness; Stage #2: With hydrogenchloride In dichloromethane; water | 60% |
Conditions | Yield |
---|---|
In dichloromethane at 25℃; for 1h; | 100% |
With water In dichloromethane at 20℃; for 0.5h; | 94% |
rhodamine B
Conditions | Yield |
---|---|
With thionyl chloride at 20℃; Inert atmosphere; | 99% |
With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; | 99% |
With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; for 2h; | 98% |
Conditions | Yield |
---|---|
In ethanol for 16h; Reflux; | 99% |
In ethanol for 12h; Reflux; | 95% |
In ethanol for 12h; Reflux; Inert atmosphere; Schlenk technique; | 95% |
Conditions | Yield |
---|---|
With hydrazine hydrate In ethanol; water for 0.333333h; Sonication; | 99% |
rhodamine B
rhodamine B hydrazide
Conditions | Yield |
---|---|
With hydrazine hydrate In ethanol for 3h; Reflux; | 97% |
With hydrazine hydrate In ethanol for 12h; Reflux; | 95% |
With hydrazine hydrate In ethanol for 12h; Reflux; | 95% |
Conditions | Yield |
---|---|
at 60℃; for 96h; | 95.5% |
rhodamine B
triethylentetramine
N-(rhodamine B)lactam-triethylenetetramine
Conditions | Yield |
---|---|
In ethanol at 80℃; Inert atmosphere; | 95% |
at 80℃; Inert atmosphere; | 95% |
In ethanol for 15h; Reflux; | 76% |
Conditions | Yield |
---|---|
In water; ethyl acetate | 95% |
Conditions | Yield |
---|---|
In ethanol for 3h; Reflux; | 94.8% |
rhodamine B
1,5-diamino-3-azapentane
N-(rhodamine B)lactam-diethylenetriamine
Conditions | Yield |
---|---|
In methanol for 13h; Reflux; | 94.6% |
In ethanol at 80℃; Inert atmosphere; | 91% |
In ethanol for 24h; Reflux; | 91% |
allyl iodid
rhodamine B
(9-(2-((allyloxy)carbonyl)phenyl)-6-(diethylamino)-3-xanthenylidene)diethylammonium chloride
Conditions | Yield |
---|---|
With caesium carbonate In N,N-dimethyl-formamide at 60℃; for 24h; Inert atmosphere; | 94.6% |
With caesium carbonate In N,N-dimethyl-formamide at 60℃; for 24h; | 88.8% |
2-[2-(2-azidoethoxy)ethoxy]ethanamine
rhodamine B
Conditions | Yield |
---|---|
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; dmap In dichloromethane at 20℃; | 94% |
Conditions | Yield |
---|---|
With sodium hydroxide In water for 2h; Inert atmosphere; | 94% |
With sodium hydroxide In water | 90% |
With sodium hydroxide | 90.2% |
With sodium hydroxide In ethyl acetate |
Conditions | Yield |
---|---|
With trichlorophosphate In 1,2-dichloro-ethane at 0 - 85℃; for 5.25h; Inert atmosphere; | 94% |
Conditions | Yield |
---|---|
at 200℃; for 2h; Inert atmosphere; | 94% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate at 20℃; | 94% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In methanol at 50℃; for 18h; Solvent; Temperature; | 93.88% |
With triethylamine In dichloromethane for 24h; Inert atmosphere; Reflux; | 44.5% |
Conditions | Yield |
---|---|
In ethanol Reflux; | 93.6% |
In ethanol for 2h; Reflux; | 62.8% |
In methanol Reflux; | |
In ethanol for 3h; Reflux; | |
In ethanol for 3h; Reflux; |
rhodamine B
2-[2-(2-azidoethoxy)ethoxy]ethanol
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide In dichloromethane at 23℃; for 12h; | 93% |
Conditions | Yield |
---|---|
With trichlorophosphate In 1,2-dichloro-ethane at 0 - 85℃; for 5.25h; Inert atmosphere; | 92% |
Conditions | Yield |
---|---|
With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 80℃; for 18h; | 92% |
rhodamine B
1-t-Butoxycarbonylpiperazine
rhodamine-N-piperazine-N-Boc
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 2h; | 91.2% |
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; | 80% |
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; | 80% |
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 24h; | 91% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 16.5h; | 91% |
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 16h; | 91% |
Stage #1: 2-methyl-2-propenoic acid 2-hydroxyethyl ester; rhodamine B With dmap; camphor-10-sulfonic acid In chloroform for 0.5h; Stage #2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In chloroform at 20℃; for 2h; | 90% |
3-acetylenephenylamine
rhodamine B
Conditions | Yield |
---|---|
With triethylamine; HATU In N,N-dimethyl-formamide at 20℃; for 16h; | 91% |
rhodamine B
N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine
N-(rhodamine B)lactam-tetraethylenepentamine
Conditions | Yield |
---|---|
In ethanol at 80℃; for 12h; Solvent; Temperature; | 90.8% |
In ethanol at 80℃; Inert atmosphere; | 87% |
at 80℃; Inert atmosphere; | 87% |
In ethanol for 12h; Reflux; | 72% |
Conditions | Yield |
---|---|
In ethanol for 12h; Reflux; | 90.8% |
Ir(P(C6H4CH3)3)2(CO)(acetone)SbF6
rhodamine B
carbonylbis(tri-p-tolylphosphine)(rhodamine)iridium hexafluoroantimonate
Conditions | Yield |
---|---|
In diethyl ether A suspension of (Ir(P(tol)3)2CO(acetone))(SbF6) in ether is treated with rhodamine followed by stirring for 5 h.; Filtration, recrystn. from dichloromethane.; | 90% |
Molecular Structure:
Molecular Formula: C28H31ClN2O3
Molecular Weight: 479.0103
IUPAC: [9-(2-Carboxyphenyl)-6-(diethylamino)xanthen-3-ylidene]-diethylazanium chloride
Synonyms of Rhodamine B (CAS NO.81-88-9): 9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride ; Ammonium, (9-(o-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)diethyl-, chloride ; C.I. Basic Violet 10 ; Ethanaminium, N-(9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethyl-, chloride (9CI) ; Xanthylium, 9-(2-carboxyphenyl)-3,6-bis(diethylamino)-, chloride ; Xanthylium, 9-(2-carboxyphenyl)-3,6-bis(diethylamino)-, chloride (1:1) ; C.I. Food Red 15 ; D&C Red No. 19
CAS NO: 81-88-9
Classification Code: Agricultural Chemical ; Experimental pesticide ; Mutation data ; Reproductive Effect ; Tumor data ; Unspecified / Unclassified pesticide
Melting point: 210-211 °C
Density: 0.79 g/mL at 20 °C
Flash Point: 12 °C
Storage temp: Store at RT.
Colour Index: 45170
Water Solubility: SOLUBLE
BRN: 4119648
Stability: Stable. Incompatible with strong oxidizing agents.
Rhodamine B (CAS NO.81-88-9) is used as dye, esp for paper, as reagent for antimony, bismuth, cobalt, niobium, gold, manganese, mercury, molybdenum, tantalum, thallium, tungsten, as biological stain.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 144mg/kg (144mg/kg) | "Recent Advances of Chemistry and Molecular Biology in Cancer Research, Insternational Symposium on Recent Advances of Chemistry and Molecular Biology in Cancer Research, Held in Beijing/China, July 23rd-26th, 1991" Dai Qianhuan, Margaret-Ann Armour and Zheng Qingying eds. Science Press Vol. -, Pg. 281, 1993. | |
mouse | LD50 | oral | 887mg/kg (887mg/kg) | Toxicological European Research. Vol. 1, Pg. 23, 1978. | |
mouse | LD50 | subcutaneous | 180mg/kg (180mg/kg) | Osaka-furitsu Koshu Eisei Kenkyusho Kenkyu Hokoku, Koshu Eisei Hen. Research Reports of the Oaka Prefectural Institute of Public Health, Public Health Section. Vol. (3), Pg. 185, 1953. | |
rat | LD50 | intraperitoneal | 112mg/kg (112mg/kg) | Toxicological European Research. Vol. 1, Pg. 23, 1978. | |
rat | LD50 | intravenous | 89mg/kg (89mg/kg) | Toxicology and Applied Pharmacology. Vol. 3, Pg. 696, 1961. | |
rat | LDLo | oral | 500mg/kg (500mg/kg) | National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 8, 1953. |
Hazard Codes of Rhodamine B (CAS NO.81-88-9): Xn,Xi,F
Risk Statements: 22-41-68-67-36-11
R22: Harmful if swallowed.
R41: Risk of serious damage to the eyes.
R68: Possible risk of irreversible effects.
R67: Vapours may cause drowsiness and dizziness.
R36: Irritating to eyes.
R11: Highly flammable.
Safety Statements: 7-16-24/25-26-36/37/39
S7: Keep container tightly closed.
S16: Keep away from sources of ignition.
S24/25: Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 2
Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Storage:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances
Handling:Wash thoroughly after handling. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
First Aid Measures:
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View