9087-70-1 powder Trypsin inhibitor 98%MIN factory
Min.Order / FOB Price:Get Latest Price
| 20 Milliliter |
FOB Price: USD 300.0000 |
- Min.Order :20 Milliliter
- Purity: 99% by HPLC
- Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram
Keywords
9087-70-1 powder 9087-70-1 factory Trypsin inhibitor 98%MIN
Quick Details
- Appearance:Solid powder
- Application:Applied in dietary supplements,pharmaceutical or cosmeticeuticals
- PackAge:aluminum foil bag,carton drum
- ProductionCapacity:5000|Gram|Month
- Storage:Sealed,light and oxygen resistant
- Transportation:by sea or air
Superiority:
Aprotinin is a competitive serine protease inhibitor. Reversibly binds to and blocks the enzymatic active site. Inhibits a range of serine proteases including trypsin, chymotrypsin, kallikrein and plasmin. Inhibits cytopathogenic effect of SARS-CoV-2 and double-stranded RNA formation in SARS-CoV-2-infected cells.
Competitive reversible inhibitor of proteolytic and esterolytic activity. A relatively heat- and acid-stable serine protease inhibitor. Forms a tight complex, blocking the active site of the enzyme. Effective at concentrations equimolar with protease. Inhibits several proteases, including coagulation factors in the prephase of blood clotting, tissue and leukocytic proteinases, chymotrypsin, trypsin (Kd = 5 x 10-14 M), plasmin (Kd = 2.3 x 10-10 M), and kallikrein (Kd = 1 x 10-7 M). Proteases not inhibited by aprotinin include Factor Xa, thrombin, pepsin, papain, and carboxypeptidases A and B. Useful in protein purification and for extending the life of cells in culture by preventing proteolytic damage.
Details:
A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION.
Aprotinin is a reversible inhibitor of serine proteases such as trypsin (Ki = 0.06 pM), chymotrypsin (Ki = 9.5 nM), and kallikrein (Ki = 0.8 nM). It is a much weaker inhibitor of thrombin (Ki = 0.1-
Proteolytic inhibitor in radioimmunoassays of polypeptide hormones.
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