1000614-08-3 Usage
Description
(S)-1-(3,5-bis(trifluoroMethyl)phenyl)-N-MethylethanaMine tosylate is a tosylate salt derivative of N-methylephedrine, belonging to the class of amine compounds. It is characterized by the presence of trifluoromethyl groups in the phenyl ring, which enhances the activity and selectivity of various drugs. The tosylate salt form improves its stability and solubility, making it a valuable chemical for drug discovery and development.
Uses
Used in Pharmaceutical Applications:
(S)-1-(3,5-bis(trifluoroMethyl)phenyl)-N-MethylethanaMine tosylate is used as an intermediate in the synthesis of various pharmaceutical compounds for enhancing their activity and selectivity. The presence of the trifluoromethyl group in the phenyl ring contributes to the improved performance of these drugs.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (S)-1-(3,5-bis(trifluoroMethyl)phenyl)-N-MethylethanaMine tosylate is used as a key compound for studying the effects of trifluoromethyl substitution on the properties and biological activities of drug candidates. This helps researchers in designing more effective and selective drugs.
Used in Drug Discovery and Development:
(S)-1-(3,5-bis(trifluoroMethyl)phenyl)-N-MethylethanaMine tosylate is utilized as a valuable chemical in the drug discovery and development process. Its improved stability and solubility in the tosylate salt form make it easier to handle and administer in experimental and clinical settings, facilitating the development of new drugs with enhanced properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1000614-08-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,6,1 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1000614-08:
(9*1)+(8*0)+(7*0)+(6*0)+(5*6)+(4*1)+(3*4)+(2*0)+(1*8)=63
63 % 10 = 3
So 1000614-08-3 is a valid CAS Registry Number.
1000614-08-3Relevant articles and documents
METHOD FOR PRODUCING OPTICALLY ACTIVE 1-(FLUORO-, TRIFLUOROMETHYL- OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVE
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Page/Page column 17-18, (2009/04/23)
There is provided a method for producing an optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy-substituted phenyl)alkylamine N-monoalkyl derivative, which includes the steps of conducting reductive alkylation of an optically active secondary amine and a formaldehyde (including an equivalent thereof) or lower aldehyde in the presence of a transition metal catalyst under a hydrogen gas atmosphere, thereby converting the secondary amine to an optically active tertiary amine of the formula, and subjecting the tertiary amine to hydrogenolysis. The target optically active compound can be produced efficiently by this production method.
