1001296-60-1

Basic information

• Product Name: (S)-(+)-phenylglycinol salt of (S)-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid
• Synonyms: (S)-(+)-phenylglycinol salt of (S)-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid
• CAS NO: 1001296-60-1
• Molecular Weight: 324.42
• Mol File: 1001296-60-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-(+)-phenylglycinol salt of (S)-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-phenylglycinol salt of (S)-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid(1001296-60-1)
• EPA Substance Registry System: (S)-(+)-phenylglycinol salt of (S)-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid(1001296-60-1)

Safety Data

• Hazardous Substances Data: 1001296-60-1(Hazardous Substances Data)

Upstream product

• 181289-15-6 (±)?3?(carbamoylmethyl)?5?methylhexanoic acid 
• 20989-17-7 (2S)-2-phenylglycinol 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF (R)-(-)-3-(CARBAMOYLMETHYL)-5-METHYLHEXANOIC ACID AND OF PREGABALIN AND SYNTHESIS INTERMEDIATES

This invention relates to the preparation of (R)-(-)-3-(carbamoylmethyl)-5- methylhexanoic acid, in particular, the resolution of the acid racemate by means of salification with optically active amines and subsequent acidification to give the (R) enantiomer of the acid; this invention also concerns the salt intermediates formed with said amines and the conversion of said (R)-(-)-3-(carbamoylmethyl)-5- methylhexanoic acid into biologically active molecules such as pregabalin.