100330-45-8

Basic information

• Product Name: (+/-)-1-(2-Phenylethyl)-3-propynyl acetate
• Synonyms: (+/-)-1-(2-Phenylethyl)-3-propynyl acetate
• CAS NO: 100330-45-8
• Molecular Weight: 202.253
• Mol File: 100330-45-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (+/-)-1-(2-Phenylethyl)-3-propynyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-1-(2-Phenylethyl)-3-propynyl acetate(100330-45-8)
• EPA Substance Registry System: (+/-)-1-(2-Phenylethyl)-3-propynyl acetate(100330-45-8)

Safety Data

• Hazardous Substances Data: 100330-45-8(Hazardous Substances Data)

Upstream product

• 99902-35-9 5-phenylpent-1-yn-3-ol 
• 108-24-7 acetic anhydride 
• 104-53-0 3-phenyl-propionaldehyde 
• 140149-77-5 5-phenyl-1-trimethylsilylpent-1-yn-3-ol 
• 110211-31-9 Acetic acid 1-phenethyl-3-trimethylsilanyl-prop-2-ynyl ester 
• 4301-14-8 acetylenemagnesium bromide 
• 75-36-5 acetyl chloride 

Downstream Products

• 143140-90-3 2-(1-acetoxy-3-(phenyl)propyl)-1,3-butadiene 
• 929606-19-9 (R)-5-phenylpent-1-yn-3-yl acetate 
• 183904-28-1 (S)-5-phenyl-1-pentyn-3-ol 
• 99902-35-9 (R)-3-hydroxy-5-phenyl-1-pentyne 
• 100330-37-8 Acetic acid 2,4-dioxo-1-phenethyl-pentyl ester 
• 1436409-05-0 C₂₁H₂₈O₂ 
• 104367-28-4 (7-methylocta-3,4-dien-1-yl)benzene 
• 104367-27-3 hepta-3,4-diene-1,7-diyldibenzene 
• 99902-35-9 5-phenylpent-1-yn-3-ol 
• 1609456-38-3 4,4,5,5-tetramethyl-2-(5-phenylpenta-1,2-dien-1-yl)-1,3,2-dioxaborolane 

Relevant articles and documents

Rhodium-Catalyzed Parallel Kinetic Resolution of Racemic Internal Allenes Towards Enantiopure Allylic 1,3-Diketones

A rare case of a parallel kinetic resolution of racemic 1,3-disubstituted allenes by means of a rhodium-catalyzed addition to 1,3-diketones furnishing enantiopure allylic 1,3-diketones is described. Mechanistic experiments demonstrate that the different allene enantiomers react in parallel to either the diastereomeric E- or Z-allylic 1,3-diketones with the same absolute configuration of the newly formed stereogenic center. A broad substrate scope demonstrates the synthetic utility of this new method.

Borylation of propargylic substrates by bimetallic catalysis. Synthesis of allenyl, propargylic, and butadienyl bpin derivatives

Bimetallic Pd/Cu and Pd/Ag catalytic systems were used for borylation of propargylic alcohol derivatives. The substrate scope includes even terminal alkynes. The reactions proceed stererospecifically with formal S N2′ pathways to give allenyl boronates. Opening of propargyl epoxides leads to 1,2-diborylated butadienes probably via en allenylboronate intermediate.

Construction of 1,5-enynes by stereospecific Pd-catalyzed allyl-propargyl cross-couplings

The palladium-catalyzed cross-coupling of chiral propargyl acetates and allyl boronates delivers chiral 1,5-enynes with excellent levels of chirality transfer and can be applied across a broad range of substrates.