99902-35-9Relevant articles and documents
Sc(OTf)3-catalyzed [3 + 2]-cycloaddition of nitrones with ynones
He, Chun-Ting,Han, Xiao-Li,Zhang, Yan-Xue,Du, Zhen-Ting,Si, Chang-Mei,Wei, Bang-Guo
supporting information, p. 457 - 466 (2021/01/29)
An efficient approach to access functionalized (2,3-dihydroisoxazol-4-yl) ketones has been developed by reacting nitrones 4 with ynones 7 or terminal ynones 10 in a one-pot fashion. The reaction went through a formal Sc(OTf)3-catalyzed [3 + 2]-cycloaddition process to generate a number of functionalized (2,3-dihydroisoxazol-4-yl) ketones 11aa-11aw, 11ba-11la and 12aa-12ae in moderate to good yields. This journal is
Synthesis of Difluorinated Dihydrobenzo[de]chromenes via Rh(III)-Catalysed C-H Couplings of 1-Naphthols with Gem-Difluoromethylene Alkynes
Li, Liping,Zhong, Xiuhua,Xu, Jiali,Gao, Hui,Zhou, Zhi,Yi, Wei
supporting information, p. 1352 - 1357 (2021/02/01)
The Rh(III)-catalysed C?H couplings of 1-naphthols with gem-difluoromethylene alkynes have been realized for the direct construction of difluorinated dihydrobenzo[de]chromenes with broad substrate/functional group compatibility and good regio-/chemoselect
Transition-Metal-Free Synthesis of Electron Rich 1,3-Dienes via Base Promoted Isomerization of Propargylic Ethers
Liu, Chunxiang,Deng, Guogang,Li, Xin,Xu, Yiren,Yu, Kaili,Chen, Wen,Zhang, Hongbin,Yang, Xiaodong
, p. 483 - 487 (2020/01/25)
Herein, a novel and scalable synthesis of electron rich 1,3-dienes based on KOtBu mediated isomerization of propargylic ether derivatives was developed. This new process features easy handling reaction conditions, transition-metal-free isomerization, high isolated yields, and most of all, it could be used for modification of natural products at late stage functionalizations.