1003312-15-9 Usage
Molecular Structure
The compound consists of a pyridine ring with a bromine atom and a methyl group at positions 3 and 4, respectively, and a methoxybenzyloxy group attached to position 2 of the pyridine ring.
Usage
Commonly used in organic synthesis and medicinal chemistry as an intermediate for the production of various pharmaceuticals and agrochemicals.
Unique Value
Its unique structure and reactivity make it valuable for the development of new compounds with potential biological activities.
Chemical Modification Opportunities
Its bromine and methoxybenzyl moieties provide opportunities for further chemical modifications to tailor its properties for specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1003312-15-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,3,3,1 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1003312-15:
(9*1)+(8*0)+(7*0)+(6*3)+(5*3)+(4*1)+(3*2)+(2*1)+(1*5)=59
59 % 10 = 9
So 1003312-15-9 is a valid CAS Registry Number.
1003312-15-9Relevant articles and documents
Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit
Hu, Essa,Tasker, Andrew,White, Ryan D.,Kunz, Roxanne K.,Human, Jason,Chen, Ning,Bürli, Roland,Hungate, Randall,Novak, Perry,Itano, Andrea,Zhang, Xuxia,Yu, Violeta,Nguyen, Yen,Tudor, Yanyan,Plant, Matthew,Flynn, Shaun,Xu, Yang,Meagher, Kristin L.,Whittington, Douglas A.,Ng, Gordon Y.
, p. 3065 - 3068 (2008)
Inhibition of c-Kit has the potential to treat mast cell associated fibrotic diseases. We report the discovery of several aminoquinazoline pyridones that are potent inhibitors of c-Kit with greater than 200-fold selectivity against KDR, p38, Lck, and Src.
KINASE INHIBITORS
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Paragraph 0203; 0204, (2016/05/02)
The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
