55404-31-4

Basic information

• Product Name: 3-BROMO-2-CHLORO-4-PICOLINE
• Synonyms: 3-BROMO-2-CHLORO-4-PICOLINE;2-CHLORO-3-BROMO-4-PICOLINE;3-BROMO-2-CHLORO-4-METHYLPYRIDINE;3-BROMO-2CHLORL-4-PICOLINE;2-Chloro-3-bromo-4-methylpyridine;3-Bromo-2-chloro-4-methyl...;3-Bromo-2-chloro-4-methylprinine;3-Bromo-2-chloro-4-methylpyridine 97%
• CAS NO: 55404-31-4
• Molecular Formula: C₆H₅BrClN
• Molecular Weight: 206.47
• Product Categories: Heterocycle-Pyridine series
• Mol File: 55404-31-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 250.3 °C at 760 mmHg
• Flash Point: 105.2 °C
• Appearance: /
• Density: 1.624 g/cm³
• Vapor Pressure: 0.0346mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 0.17±0.10(Predicted)
• CAS DataBase Reference: 3-BROMO-2-CHLORO-4-PICOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-CHLORO-4-PICOLINE(55404-31-4)
• EPA Substance Registry System: 3-BROMO-2-CHLORO-4-PICOLINE(55404-31-4)

Safety Data

• Hazardous Substances Data: 55404-31-4(Hazardous Substances Data)

Usage

General Description

3-Bromo-2-chloro-4-picoline is a chemical compound with the formula C6H4BrClNO. It is a member of the picoline family, which are heterocyclic organic compounds containing a pyridine ring. This particular compound is characterized by the presence of bromine and chlorine substituents on the pyridine ring. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it can be used as a building block in organic synthesis, particularly in the production of complex organic molecules. The compound is typically handled and used in a controlled laboratory environment due to its potential hazards and reactivity.

InChI:InChI=1/C6H5BrClN/c1-4-2-3-9-6(8)5(4)7/h2-3H,1H3

Upstream product

• 133627-45-9 3-Amino-2-chloro-4-methylpyridine 
• 3430-22-6 3-Bromo-4-methylpyridin 
• 17117-15-6 3-bromo-4-methyl-1-oxidopyridin-1-ium 

Downstream Products

• 1003312-15-9 2-(4-methoxybenzyloxy)-3-bromo-4-methylpyridine 
• 18368-59-7 3-bromo-4-methyl-1H-pyridin-2-one 
• 851607-30-2 3-bromo-5-chloro-2-methoxy-4-methylpyridine 
• 1429510-98-4 5-(2,4-dimethoxybenzyl)-7-(2-methoxy-4-methylpyridin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[4,3-c]quinolin-4(5H)-one 
• 1429510-99-5 5-(2,4-dimethoxybenzyl)-7-(2-ethoxy-4-methylpyridin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[4,3-c]quinolin-4(5H)-one 

Relevant articles and documents

MACROCYCLIC DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The invention relates to compounds of formula (Φ) as further defined herein and to the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to the uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma kinase (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.