100562-46-7Relevant articles and documents
Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3)
Kuduk, Scott D.,Chang, Ronald K.,Wai, Jenny M.-C.,Di Marco, Christina N.,Cofre, Victoria,DiPardo, Robert M.,Cook, Sean P.,Cato, Matthew J.,Jovanovska, Aneta,Urban, Mark O.,Leitl, Michael,Spencer, Robert H.,Kane, Stefanie A.,Hartman, George D.,Bilodeau, Mark T.
scheme or table, p. 4059 - 4063 (2010/04/05)
A series of indole amidines modified at the 2-position of the indole ring were evaluated as inhibitors of Acid-Sensing Ion Channel-3 (ASIC3), a novel target for the treatment of chronic pain.