83515-06-4

Basic information

• Product Name: 1H-INDOLE, 5-BROMO-2-PHENYL-
• Synonyms: 1H-INDOLE, 5-BROMO-2-PHENYL-
• CAS NO: 83515-06-4
• Molecular Formula: C₁₄H₁₀BrN
• Molecular Weight: 272.14
• Mol File: 83515-06-4.mol
• Article Data: 55

Chemical Properties

• Melting Point: 195-196℃
• Appearance: /
• Density: 1.484
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-INDOLE, 5-BROMO-2-PHENYL-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDOLE, 5-BROMO-2-PHENYL-(83515-06-4)
• EPA Substance Registry System: 1H-INDOLE, 5-BROMO-2-PHENYL-(83515-06-4)

Safety Data

• Hazardous Substances Data: 83515-06-4(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-phenyl-1H-indole is a chemical compound with the molecular formula C14H10BrN. It is a derivative of indole, a heterocyclic aromatic organic compound, and is characterized by the presence of a bromine atom and a phenyl group attached to the indole ring. 1H-INDOLE, 5-BROMO-2-PHENYL- has been of interest in pharmaceutical research due to its potential biological activities and medicinal properties, including its role as a building block for the synthesis of various bioactive molecules. It has also been studied for its potential application in the development of pharmaceutical drugs and agrochemicals. Additionally, it has been investigated for its potential use as a dye intermediate and in organic synthesis.

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Downstream Products

• 83515-07-5 5-Bromo-2-phenyl-3-nitrosoindole 
• 83515-10-0 5-bromo-2-phenyl-3H-indol-3-one 
• 100562-46-7 2-Phenyl-1H-indole-5-carboximidic acid ethyl ester 
• 83515-09-7 5-Bromo-2-phenyl-3-iminoindole 
• 83515-08-6 5-Bromo-2-phenyl-3-aminoindole 
• 83515-20-2 5-Bromo-2-phenylindol-3-one semicarbazone 
• 83515-23-5 5-Bromo-2-phenylindol-3-one thiosemicarbazone 
• 83515-11-1 9-Bromo-5a-phenyl-5a,6-dihydro-5H-indolo[2,3-b]quinoxaline 
• 83515-12-2 9-Bromo-2-chloro-5a-phenyl-5a,6-dihydro-5H-indolo[2,3-b]quinoxaline 
• 83515-17-7 9-Bromo-6-nitro-6a-phenyl-6,12a-dihydro-6aH-indolo[1,2-a]quinolin-7-one 
• 1086450-14-7 5-(5-(5-(5,5-dimethyl-1,3-dioxan-2-yl)thiophen-2-yl)thiophen-2-yl)-2-phenylindole 
• 1364952-72-6 N-(2-bromo-1-(5-bromo-2-phenyl-1H-indol-1-yl)-2,2-difluoroethylidene)-4-methoxyaniline 
• 1364953-45-6 N-(10-bromo-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline 
• 1363261-49-7 (S)-N(α)-acetyl-5-bromo-2-phenyltryptophan methyl ester 

Relevant articles and documents

Acid-catalyzed cleavage of C-C bonds enables atropaldehyde acetals as masked C2 electrophiles for organic synthesis

Acid-catalyzed tandem reactions of atropaldehyde acetals were established for the synthesis of three important molecules, 2,2-disubstituted indolin-3-ones, naphthofurans and stilbenes. The synthesis was realized using novel reaction cascades, which involved the same two initial steps: (i) SN2′ substitution, in which the atropaldehyde acted as an electrophile; and (ii) oxidative cleavage of the carbon-carbon bond of the generated phenylacetaldehyde-type products. Compared with literature methods, the present protocol not only avoided the use of expensive noble metal catalysts, but also enabled a simple operation.

Copper-Catalyzed Enantioselective C-H Arylation between 2-Arylindoles and Hypervalent Iodine Reagents

The copper-catalyzed enantioselective C-H arylation between 2-arylindoles and hypervalent iodine reagents has been successfully developed, which provides a convenient and economical route to the highly atroposelective synthesis of axially chiral indole de

Iminyl-radicals by electrochemical decarboxylation of α-imino-oxy acids: construction of indole-fused polycyclics

Iminyl radicals are reactive intermediates that can be used for the construction of various valuable heterocycles. Herein, the electrochemical decarboxylation of α-imino-oxy acids for the generation of iminyl radicals has been accomplished under exogenous-oxidant- and metal-free conditions through the use ofnBu4NBr as a mediator. The resulting iminyl radicals undergo intramolecular cyclization smoothly with the adjacent (hetero)arenes to afford a series of indole-fused polycyclic compounds.