83515-10-0

Basic information

• Product Name: 5-bromo-2-phenyl-3H-indol-3-one
• Synonyms: 5-bromo-2-phenyl-3H-indol-3-one
• CAS NO: 83515-10-0
• Molecular Weight: 286.128
• Mol File: 83515-10-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-phenyl-3H-indol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-phenyl-3H-indol-3-one(83515-10-0)
• EPA Substance Registry System: 5-bromo-2-phenyl-3H-indol-3-one(83515-10-0)

Safety Data

• Hazardous Substances Data: 83515-10-0(Hazardous Substances Data)

Upstream product

• 83515-07-5 5-Bromo-2-phenyl-3-nitrosoindole 
• 83515-08-6 5-Bromo-2-phenyl-3-aminoindole 
• 83515-06-4 5-bromo-2-phenylindole 
• 83515-09-7 5-Bromo-2-phenyl-3-iminoindole 

Downstream Products

• 83515-17-7 9-Bromo-6-nitro-6a-phenyl-6,12a-dihydro-6aH-indolo[1,2-a]quinolin-7-one 
• 83515-20-2 5-Bromo-2-phenylindol-3-one semicarbazone 
• 83515-23-5 5-Bromo-2-phenylindol-3-one thiosemicarbazone 
• 83515-11-1 9-Bromo-5a-phenyl-5a,6-dihydro-5H-indolo[2,3-b]quinoxaline 
• 83515-12-2 9-Bromo-2-chloro-5a-phenyl-5a,6-dihydro-5H-indolo[2,3-b]quinoxaline 

Relevant articles and documents

Multi-site cyclization via initial C-H activation using a rhodium(III) catalyst: Rapid assembly of frameworks containing indoles and indolines

Tandem multi-site cyclization triggered by Rh(III)-catalyzed C-H activation has been achieved for highly efficient synthesis of spirocycle indolin-3-one (C2-cyclization), benzo[a]carbazole (C3-cyclization) and an unusual indoxyl core (N1-cyclization). In particular, the synthesis of pseudo-indoxyl is typically completed within 10 min, and the reaction tolerates air, water and a range of solvents.

An asymmetric normal-electron-demand aza-Diels-Alder reaction via trienamine catalysis

An asymmetric normal-electron-demand aza-Diels-Alder cycloaddition of 2-aryl-3H-indol-3-ones and 2,4-dienals was explored via trienamine catalysis of a chiral secondary amine. Multifunctional tricyclic polyhydropyrido[1,2-a] indoles were efficiently constructed in good stereoselectivity (up to 92% ee, >19:1 dr).

Synthesis and Reactions of 2-Phenylindol-3-ones

2-Phenyl-3-aminoindoles (2a-d) have been synthesised and converted into the corresponding 2-phenylindol-3-ones (4a-d), which on reaction with o-phenylenediamine (5a,b) and nitrostyrene give 9-substituted 5H-5a,6-dihydro-5a-phenylindoloquinoxalines