122212-34-4Relevant articles and documents
Total synthesis of (-)-21-isopentenylpaxilline.
Smith 3rd., Amos B,Cui, Haifeng
, p. 587 - 590 (2003)
[structure: see text] The total synthesis of (-)-21-isopentenylpaxilline (1) has been achieved. Key elements of the synthesis include the stereocontrolled construction of the advanced eastern hemisphere (-)-5, a highly efficient union of the eastern and w
Mixed Copper, Zinc 2-Amino Benzylic Organometallics as Efficient Reagents for the Synthesis of Heterocycles
Chen, Gu Huai,Hoechstetter, Craig,Knochel, Paul
, p. 4795 - 4798 (2007/10/02)
The mixed copper, zinc benzylic organometallics 1a-1c react efficiently with various electrophiles.By the reaction with acylchlorides, highly functionalized 2-substituted indoles are produced.The treatment of 1a with allylic bromides, 3-iodo-cyclohexenone and ethyl propiolate furnishes polyfunctionalized anilines.Several of them could be converted into five or seven-membered heterocycles.