126742-81-2Relevant articles and documents
Mixed Copper, Zinc 2-Amino Benzylic Organometallics as Efficient Reagents for the Synthesis of Heterocycles
Chen, Gu Huai,Hoechstetter, Craig,Knochel, Paul
, p. 4795 - 4798 (2007/10/02)
The mixed copper, zinc benzylic organometallics 1a-1c react efficiently with various electrophiles.By the reaction with acylchlorides, highly functionalized 2-substituted indoles are produced.The treatment of 1a with allylic bromides, 3-iodo-cyclohexenone and ethyl propiolate furnishes polyfunctionalized anilines.Several of them could be converted into five or seven-membered heterocycles.