221353-39-5

Basic information

• Product Name: Ethyl 4-bromo-(2-phenylethynyl)phenylcarbamate
• Synonyms: Ethyl 4-bromo-(2-phenylethynyl)phenylcarbamate
• CAS NO: 221353-39-5
• Molecular Weight: 344.208
• Mol File: 221353-39-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethyl 4-bromo-(2-phenylethynyl)phenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4-bromo-(2-phenylethynyl)phenylcarbamate(221353-39-5)
• EPA Substance Registry System: Ethyl 4-bromo-(2-phenylethynyl)phenylcarbamate(221353-39-5)

Safety Data

• Hazardous Substances Data: 221353-39-5(Hazardous Substances Data)

Upstream product

• 112671-47-3 ethyl (4-bromo-2-iodophenyl)carbamate 
• 536-74-3 phenylacetylene 

Downstream Products

• 83515-06-4 5-bromo-2-phenylindole 

Relevant articles and documents

Convenient synthesis of 2-substituted indoles from 2-ethynylanilines with tetrabutylammonium fluoride

The cyclization reaction of various 2-ethynylanilines, which were easily synthesized from 2-haloanilines by the palladium-catalyzed reaction with terminal alkynes, with tetrabutylammonium fluoride (TBAF) to yield 2-substituted indoles proceeded at refluxing or room temperature in THF in excellent yields without affecting the bromo, chloro, cyano, ethoxycarbonyl, and ethynyl groups.