1009-01-4

Basic information

• Product Name: Methanesulfonic acid 2-methylphenyl ester
• Synonyms: Methanesulfonic acid 2-methylphenyl ester
• CAS NO: 1009-01-4
• Molecular Formula: C₈H₁₀O₃S
• Molecular Weight: 186.23
• Mol File: 1009-01-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methanesulfonic acid 2-methylphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid 2-methylphenyl ester(1009-01-4)
• EPA Substance Registry System: Methanesulfonic acid 2-methylphenyl ester(1009-01-4)

Safety Data

• Hazardous Substances Data: 1009-01-4(Hazardous Substances Data)

Usage

General Description

Methanesulfonic acid 2-methylphenyl ester, also known as toluenesulfonic acid methyl ester, is a clear, colorless liquid with a sweet, pungent odor. It is commonly used as a strong acid catalyst in various chemical reactions, such as esterifications, polymerizations, and alkylation reactions. This chemical is also utilized as a solvent and as an intermediate in the production of pharmaceuticals, dyes, and fragrances. It is important to handle this chemical with caution, as it can cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Additionally, it is highly flammable and should be stored and handled in a well-ventilated area away from heat and sources of ignition.

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 95-48-7 ortho-cresol 
• 75-75-2 methanesulfonic acid 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 89929-89-5 2-(3-methylphenyl)furan 
• 38527-54-7 2-(2'-methylphenyl)furan 
• 85553-43-1 2-(3-methylphenyl)thiophene 
• 99846-56-7 2-(2-methylphenyl)thiophene 
• 95-47-6 o-xylene 
• 33388-67-9 (2-methyl-phenyl)-(piperidin-1-yl)methanone 
• 643-58-3 2-methylbiphenyl 
• 91994-11-5 5,5-dimethyl-2-(o-tolyl)-1,3,2-dioxaborinane 
• 138350-83-1 N-(tert-butoxycarbonyl)-2-methylbenzylamine 
• 1390631-73-8 C₁₅H₁₇NO 
• 32959-60-7 2-(2-methylphenyl)-1,3-benzoxazole 
• 529-19-1 2-Methylbenzonitrile 
• 354120-51-7 5-methyl-2-(2-methylphenyl)-1,3-benzoxazole 

Relevant articles and documents

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Cyanation of unactivated aryl chlorides and aryl mesylates catalyzed by palladium and hemilabile MOP-type ligands

Palladium-catalyzed cyanation of aryl halides and pseudo halides with potassium hexacyanoferrate is described employing the hemilabile, bulky, and electron-rich MOP-type ligands. When the mixture of t-BuOH and H2O was used as the solvent and K2CO3 as the base, the MOP-type ligands showed high efficiency for the palladium-catalyzed cyanation. The effect of ligand structure was studied in detail, and 2-di-tert-butylphosphino-2′-isopropoxy-1,1′-binaphthyl was the more effective for the cyanation. The catalyst system allows the cyanation of unactivated aryl chlorides, and even aryl mesylates to occur in good yields. Furthermore, the reactivity of different arylated reagents in the catalytic system was found to be: ArBr > ArCl >> ArOMs > ArOSO2Im > ArOSO2NMe2.

Neopentylglycolborylation of aryl mesylates and tosylates catalyzed by Ni-based mixed-ligand systems activated with Zn

(Chemical Presented) The mixed-ligand system NiCl2(dppp)/dppf is shown to be an effective catalyst for the neopentylglycolborylation of ortho-, meta-, and para-substituted electron-rich and electrondeficient aryl mesylates and tosylates. The ad