100994-06-7

Basic information

• Product Name: EtO₂CCHC(Me)(o-MeC₆H₄)
• Synonyms: EtO₂CCHC(Me)(o-MeC₆H₄)
• CAS NO: 100994-06-7
• Molecular Weight: 204.269
• Mol File: 100994-06-7.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: EtO₂CCHC(Me)(o-MeC₆H₄)(CAS DataBase Reference)
• NIST Chemistry Reference: EtO₂CCHC(Me)(o-MeC₆H₄)(100994-06-7)
• EPA Substance Registry System: EtO₂CCHC(Me)(o-MeC₆H₄)(100994-06-7)

Safety Data

• Hazardous Substances Data: 100994-06-7(Hazardous Substances Data)

Upstream product

• 105-36-2 ethyl bromoacetate 
• 577-16-2 2-Methylacetophenone 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 141-97-9 ethyl acetoacetate 
• 932-31-0 ortho-tolylmagnesium bromide 
• 52883-70-2 ethyl (E)-3-(pivaloyloxy)but-2-enoate 
• 84109-17-1 2-methylphenylzinc chloride 
• 1474-78-8 triethyl phosphonoformate 
• 4341-76-8 Ethyl 2-butynoate 
• 16419-60-6 2-Methylphenylboronic acid 
• 95-46-5 2-methylphenyl bromide 
• 623-70-1 ethyl (E)-crotonate 

Downstream Products

• 1174270-30-4 (E)-3-(o-tolyl)but-2-en-1-ol 
• 1374647-36-5 (E)-1-(4-bromobut-2-en-2-yl)-2-methylbenzene 

Relevant articles and documents

Cobalt-Catalyzed Asymmetric 1,4-Hydroboration of Enones with HBpin

Herein, a series of new 8-OIQ cobalt complexes were synthesized and used for cobalt-catalyzed chemo- and enantioselective 1,4-hydroboration of enones with HBpin to access chiral β,β-disubstituted ketones with good to excellent chemo- and enantioselectivties. This protocol is operationally simple and shows a broad substrate scope.

Catalytic Asymmetric Transfer Hydrogenation of trans-Chalcone Derivatives Using BINOL-derived Boro-phosphates

Chiral phosphoric-acid-catalyzed asymmetric reductions of trans-chalcones have been investigated in this work. A BINOL-derived boro-phosphate-catalyzed asymmetric transfer hydrogenation of the carbon-carbon double bond of trans-chalcone derivatives employing borane as a hydride source was realized. This methodology provides a convenient procedure to access chiral dihydrochalone derivatives in high yields and with high enantioselectivities under mild conditions.

Copper-Photocatalyzed Contra-Thermodynamic Isomerization of Polarized Alkenes

The contra-thermodynamic isomerization of α- and β-substituted cinnamate derivatives catalyzed by the Cu(OAc)2/rac-BINAP complex under blue light irradiation is reported. The use of an oxazolidinone template, which favored the complexation of the copper catalyst to the substrate, allowed the E → Z isomerization of the catalytically formed chromophore under simple and robust reaction conditions in good to excellent ratios. The mechanism of this process based on the transient formation of a chromophore was also studied.