101422-65-5Relevant articles and documents
An unprecedented approach to the Gabriel amine synthesis utilizing tosylhydrazones as alkylating agents
Yadav, Arvind K.,Yadav, Lal Dhar S.
, p. 34764 - 34767 (2014/11/08)
A new and one-pot version of the Gabriel phthalimide amine synthesis utilizing carbonyl compounds as alkylating agents via their tosylhydrazone surrogates is disclosed. The alkylation involves copper catalysed carbene insertion into the N-H bond of phthalimide. Basically, the protocol also offers a powerful tool for deoxygenative hydroamination of carbonyl compounds.