1017581-68-8

Basic information

• Product Name: [2-(3,4-dimethoxyphenylethynyl)-5-fluorophenyl]acetonitrile
• Synonyms: [2-(3,4-dimethoxyphenylethynyl)-5-fluorophenyl]acetonitrile
• CAS NO: 1017581-68-8
• Molecular Weight: 295.313
• Mol File: 1017581-68-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-(3,4-dimethoxyphenylethynyl)-5-fluorophenyl]acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(3,4-dimethoxyphenylethynyl)-5-fluorophenyl]acetonitrile(1017581-68-8)
• EPA Substance Registry System: [2-(3,4-dimethoxyphenylethynyl)-5-fluorophenyl]acetonitrile(1017581-68-8)

Safety Data

• Hazardous Substances Data: 1017581-68-8(Hazardous Substances Data)

Upstream product

• 4302-52-7 4-ethynylveratrole 
• 127792-49-8 2-(2-bromo-5-fluorophenyl)acetonitrile 

Downstream Products

• 1017581-72-4 2-[2-(3,4-dimethoxyphenylethynyl)-5-fluorophenyl]ethylamine 

Relevant articles and documents

Synthesis of benzylisoquinoline derivatives possessing electron-withdrawing substituents on the benzene ring of the isoquinoline skeleton

3,4-Dihydrobenzylisoquinolines and 1,2,3,4-tetrahydrobenzyl-isoquinolines possessing electron withdrawing substituents on the benzene ring of the isoquinoline framework are easily accessible by a synthetic approach that takes advantage of a Sonogashira coupling to build up the C1-C8a bond of the isoquinoline skeleton and a Ti-catalyzed intramolecular hydroamination of an alkyne to close the heterocyclic ring.