10236-60-9

Basic information

• Product Name: 2,3-Dichlorophenylacetic acid
• Synonyms: 2,3-DICHLOROPHENYLACETIC ACID 99%;2,3-Dichlorobenzeneacetic acid;2,3-Dichlorophenylacetic acid,97%;3-Dichlorophenylacetic acid;2,3-Dichlorophenylacetic acid, 97% 5GR;2-(2,3-Dichlorophenyl)acetic acid;2,3-DICHLOROPHENYLACETIC ACID;RARECHEM AL BO 1228
• CAS NO: 10236-60-9
• Molecular Formula: C₈H₆Cl₂O₂
• Molecular Weight: 205.04
• Product Categories: Acids and Derivatives;Aromatic Phenylacetic Acids and Derivatives
• Mol File: 10236-60-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 130-135 °C
• Boiling Point: 328 °C at 760 mmHg
• Flash Point: 152.1 °C
• Appearance: White/Powder
• Density: 1.456 g/cm³
• Vapor Pressure: 7.9E-05mmHg at 25°C
• Solubility: soluble in Methanol
• PKA: 3.87±0.10(Predicted)
• CAS DataBase Reference: 2,3-Dichlorophenylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dichlorophenylacetic acid(10236-60-9)
• EPA Substance Registry System: 2,3-Dichlorophenylacetic acid(10236-60-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-22
• Safety Statements: 37/39-26-39-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 10236-60-9(Hazardous Substances Data)

Usage

Chemical Properties

white powder

InChI:InChI=1/C8H6Cl2O2/c9-6-3-1-2-5(8(6)10)4-7(11)12/h1-3H,4H2,(H,11,12)/p-1

Upstream product

• 50-45-3 2,3-dichlorbenzoic acid 
• 3218-45-9 2,3-dichlorophenylacetonitrile 
• 32768-54-0 2,3-dichlorotoluene 
• 57915-78-3 1-(bromomethyl)-2,3-dichlorobenzene 
• 442628-43-5 2,3-dichlorobenzyl methanesulphonate 
• 38594-42-2 2,3-dichlorobenzyl alcohol 
• 2905-54-6 2,3-Dichlorobenzoic acid methyl ester 

Downstream Products

• 82302-32-7 2-(2,3-dichlorophenyl)acetyl chloride 
• 1020846-47-2 2-(2,3-dichlorophenyl)-N-(2-hydroxyethyl)-N-methyl-acetamide 
• 1310687-84-3 C₂₅H₂₈Cl₃N₃O₂ 
• 1262107-06-1 5-chloro-2-(2,3-dichlorophenyl)pentanoic acid 
• 1262106-44-4 8-(2,3-dichlorophenyl)-3-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine 
• 1262107-05-0 2-[4-chloro-1-(2,3-dichlorophenyl)butyl]-5-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]-1,3,4-oxadiazole 
• 1428640-32-7 C₁₅H₁₅Cl₂N₅ 
• 956026-43-0 1-tert-butyl-3-(2,3-dichlorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1428640-45-2 C₁₅H₁₆Cl₂N₄ 
• 1428640-56-5 C₁₂H₉Cl₂N₅ 
• 1434517-96-0 (R)-4-benzyl-3-(2-(2,3-dichlorophenyl)acetyl)oxazolidin-2-one 
• 1434517-97-1 (4R)-4-benzyl-3-(2-(2,3-dichlorophenyl)propanoyl)oxazolidin-2-one 
• 1239016-39-7 (R)-2-(2,3-dichlorophenyl)propanoic acid 
• 1434517-76-6 (R)-2-(2,3-dichlorophenyl)-N-(2-(pyridine-4-yl)benzo[d]oxazol-5-yl)propanamide 

Relevant articles and documents

Novel piperidinecarboxamide derivatives, method for preparing same and pharmaceutical compositions containing same

The invention relates to compounds of formula: as well as their salts with inorganic or organic acids, their solvates and/or their hydrates, which exhibit a very high affinity both for the human NK2 receptors for neurokinin A and for the human NK3 receptors for neurokinin B and are antagonists of the said receptors. The invention also relates to their method of preparation, the pharmaceutical compositions containing them and their use for the preparation of medicaments.

METABOLISM OF CHLOROPHENYLALANINES IN CROP AND WEED PLANTS IN RELATION TO THE FORMATION OF POTENTIAL HERBICIDAL END PRODUCTS

Metabolism of 12 synthetic D,L-chlorophenylalanines has been examined in several crop and weed plants.Twenty-five gram samples of excised shoots or leaves of bushbean, soybean, corn, pigweed, lambsquarters, and giant foxtail were allowed to metabolize 10-4 M solutions of the D,L-chlorophenylalanines for 24 hr in continuous light.The plant samples were then extracted in 80percent methanol and the soluble acidic metabolites fractionated into ether.Each ether concentrate was partially purified by fractional elution from a PrepSep C18 coloumn and then analysed by HPLC.Collected fractions were esterified with pentafluorobenzylbromide and examined by GC-MS to demonstrate the presence of PFB-esters of chlorophenylacetic, chlorobenzoic and/or chlorocinnamic acids.Since certain of these metabolites are known to be potent plant growth-regulators and herbicides, the results are discussed in relation to the potantial herbicidal action of certain chlorophenylalanines by the mechanism of 'lethal synthesis'.Key Word Index - Phaseolus vulgaris; Glycine max.; Leguminosae; Zea mays; Amaranthus retroflexus; Chenopodium album; Setaria faberii; metabolism; D,L-chlorophenylalanines; chlorophenylacetic acids; chlorobenzoic acids; chlorocinnamic acids; growth regulators.