1026-05-7

Basic information

• Product Name: (2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE
• Synonyms: AKOS BBS-00005674;(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE;ASISCHEM N44996;N-(2-METHYL-1,2,3,4-TETRAHYDRO-4-QUINOLINYL)-N-PHENYLAMINE;2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-aMine
• CAS NO: 1026-05-7
• Molecular Formula: C₁₆H₁₈N₂
• Molecular Weight: 238.33
• Mol File: 1026-05-7.mol
• Article Data: 16

Chemical Properties

• Melting Point: 126 °C
• Boiling Point: 400.4±44.0 °C(Predicted)
• Appearance: /
• Density: 1.097±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.16±0.60(Predicted)
• CAS DataBase Reference: (2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE(1026-05-7)
• EPA Substance Registry System: (2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE(1026-05-7)

Safety Data

• Hazardous Substances Data: 1026-05-7(Hazardous Substances Data)

Usage

General Description

(2-Methyl-1,2,3,4-tetrahydro-quinolin-4-yl)-phenyl-amine is a chemical compound that belongs to the class of phenylamines. It is a derivative of tetrahydroquinoline and contains a phenyl group attached to the amine functionality. (2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE is used in the synthesis of various pharmaceuticals and organic compounds. It has potential applications in medicinal chemistry and drug discovery due to its structural features and potential biological activities. Additionally, it may also have uses in organic synthesis and as a building block for the construction of more complex molecules.

Upstream product

• 75-07-0 acetaldehyde 
• 62-53-3 aniline 
• 74-86-2 acetylene 
• 88-12-0 1-ethenyl-2-pyrrolidinone 
• 2235-00-9 vinylcaprolactam 
• 3195-78-6 N-vinyl-N-methylacetamide 
• 5202-78-8 acetylaminoethylene 
• 13162-05-5 n-vinylformamide 
• 109-92-2 ethyl vinyl ether 
• 111-34-2 -butyl vinyl ether 
• 1484-13-5 9-vinyl-9H-carbazole 
• 709-80-8 methyl N-(2, 6-dimethylphenyl)alaninate 
• 15727-49-8 N-Phenylalanin 
• 103-69-5 N-ethyl-N-phenylamine 

Downstream Products

• 91-63-4 2-methylquinoline 
• 13125-50-3 (+/-)-N-(1-acetyl-2c-methyl-1,2,3,4-tetrahydro-[4r]quinolyl)-N-phenyl-acetamide 
• 857-45-4 (+/-)-4c-anilino-1-benzoyl-2r-methyl-1,2,3,4-tetrahydro-quinoline 
• 303226-75-7 (4-Anilino-2-methyl-3,4-dihydro-1(2H)-quinolinyl)(4-chlorophenyl)methanone 
• 300690-21-5 cis-(4-Anilino-2-methyl-3,4-dihydro-1(2H)-quinolinyl)(thien-2-yl)methanone 
• 857-45-4 (+/-)-4t-anilino-1-benzoyl-2r-methyl-1,2,3,4-tetrahydro-quinoline 
• 103-69-5 N-ethyl-N-phenylamine 
• 62-53-3 aniline 
• 1026-05-7 trans-2-methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine 
• 1026-05-7 cis-2-methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine 

Relevant articles and documents

Facile synthesis of 2-methylquinolines from anilines on mesoporous N-doped TiO2 under UV and visible light

Nitrogen-doped TiO2 was synthesized by a simple wet method using a nitrogen precursor hydrazine hydrate and nano TiO2. This photocatalyst was characterized by X-ray diffraction, highresolution transmission electron microscopy, diffused reflectance spectra, photoluminescence, and X-ray photoelectron spectroscopy. XPS analysis indicates the incorporation of anionic nitrogen in TiO2 lattice as O-Ti-N linkage. N2 adsorption-desorpion isotherm indicates the mesoporous nature of N-TiO2 with the surface area 130.0 m2/g. Sizes of N-TiO2 particles are found to be in the range of 5-30 nm by HRTEM images. DRS spectra reveal the extended absorption to the visible range. N-TiO2 is found to be more efficient than Ag-TiO2, Au-TiO2, and Pt-TiO2 in quinaldine synthesis under visible light. Copyright Taylor & Francis Group, LLC.

Radical cation salts induced domino reaction of anilines with enol ethers: Synthesis of 1,2,3,4-tetrahydroquinoline derivatives

A domino reaction of anilines with cyclic and acyclic enol ethers induced by catalytic amounts of TBPA?+ (5 mol%) was investigated and a series of 2,4-disubstituted-1,2,3,4-tetrahydroquinolines were synthesized. Different from cyclic enol ethers, when acyclic enol ethers were used in the reaction, they serve as surrogates of acetaldehyde, producing a series of 2-methyl-4-anilino-1,2,3,4-tetrahydroquinolines. A single electron transfer mechanism was proposed to rationalize the products formation.

Sequential Photoredox Catalysis for Cascade Aerobic Decarboxylative Povarov and Oxidative Dehydrogenation Reactions of N-Aryl α-Amino Acids

A visible-light-driven sequential photoredox catalysis to allow N-aryl α-amino acids to experience efficient cascade aerobic decarboxylative Povarov and oxidative dehydrogenation (ODH) reactions is described. With a dicyanopyrazine-derived chromophore (DP

Method for synthesizing 1,2,3,4-tetrahydroquinoline compounds in mode that decarboxylation of amino acid is catalyzed by visible light

The invention relates to a method for synthesizing 1,2,3,4-tetrahydroquinoline compounds in the mode that decarboxylation of amino acid is catalyzed by visible light. The method is characterized in that in an air atmosphere, the N-phenyl amino acidic compounds shown in the formula I, an organic photocatalyst DPZ and 4-molecular sieve are dissolved in an organic solvent, stirred and reacted for atleast 5 hours at the temperature of 20-30 DEG C under the irradiation of the visible light, separation and purification are conducted, and then the tetrahydroquinoline compounds shown in the formula II are obtained, wherein in the formula I and the formula II (the formulas are shown in the description), R is representative for any one of hydrogen, halogen, alkyl, phenyl and alkoxy, R1 is representative for any one of hydrogen, methyl, n-propyl and phenyl, alkyl is representative for methyl or ethyl or normal-butyl or benzyl, and aryl is representative for substituted phenyl or 4-tert-butyl phenyl. According to the method, substrates are simple, reaction conditions are mild, the usage amount of the catalyst is low, the yield is high, and no metal participates in a reaction.