1026161-23-8

Basic information

• Product Name: 6-Chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3-carbonyl chloride
• Synonyms: 6-Chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3-carbonyl chloride
• CAS NO: 1026161-23-8
• Molecular Weight: 332.186
• Mol File: 1026161-23-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-Chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3-carbonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3-carbonyl chloride(1026161-23-8)
• EPA Substance Registry System: 6-Chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3-carbonyl chloride(1026161-23-8)

Safety Data

• Hazardous Substances Data: 1026161-23-8(Hazardous Substances Data)

Upstream product

• 71-43-2 benzene 
• 118-45-6 4-chlorophthalic anhydride 
• 142256-41-5 6-chloro-1-oxo-4-phenyl-1H-isochromene-3-carboxylic acid 
• 33184-56-4 2-benzoyl-4-chlorobenzoic acid 
• 142256-43-7 6-chloro-1,2-dihydro-2-methyl-1-oxo-4-phenyl-3-isoquinolinecarboxylic acid 

Downstream Products

• 1332697-21-8 diethyl 2-[(6-chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydroisoquinolin-3-yl)methyl]propane-1,3-dioate 
• 1332697-20-7 3-(6-chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydroisoquinolin-3-yl)propanoic acid 
• 1332697-19-4 tert-butyl [2-(6-chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl]carbamate 
• 1332696-99-7 3-(2-aminoethyl)-6-chloro-2-methyl-4-phenylisoquinolin-1(2H)-one hydrochloride 

Relevant articles and documents

Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: A new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554

The design, synthesis, and structure-activity relationships of a new class of potent and orally active non-peptide dipeptidyl peptidase IV (DPP-4) inhibitors, 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones, are described. We hypothesized that the 4-ph