142256-43-7Relevant articles and documents
Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: A new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554
Banno, Yoshihiro,Miyamoto, Yasufumi,Sasaki, Mitsuru,Oi, Satoru,Asakawa, Tomoko,Kataoka, Osamu,Takeuchi, Koji,Suzuki, Nobuhiro,Ikedo, Koji,Kosaka, Takuo,Tsubotani, Shigetoshi,Tani, Akiyoshi,Funami, Miyuki,Tawada, Michiko,Yamamoto, Yoshio,Aertgeerts, Kathleen,Yano, Jason,Maezaki, Hironobu
, p. 4953 - 4970 (2011/10/04)
The design, synthesis, and structure-activity relationships of a new class of potent and orally active non-peptide dipeptidyl peptidase IV (DPP-4) inhibitors, 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones, are described. We hypothesized that the 4-ph
Heterocyclic amine, derivatives, their production and use
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, (2008/06/13)
A novel heterocyclic amine derivative of the general formula: STR1 wherein a ring A and a ring B stand independently for an optionally substituted benzene ring, Z° stands for O or S or STR2 stands for --CH2 --, X stands for O, S or NR1/su