1026361-55-6

Basic information

• Product Name: (1S,3aS,3bS,9aR,9bS,11aS)-1-{[Bis-(4-chloro-phenyl)-methyl]-carbamoyl}-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,7,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridine-5-carboxylic acid tert-butyl ester
• CAS NO: 1026361-55-6
• Molecular Weight: 651.673
• Mol File: 1026361-55-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,3aS,3bS,9aR,9bS,11aS)-1-{[Bis-(4-chloro-phenyl)-methyl]-carbamoyl}-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,7,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridine-5-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3aS,3bS,9aR,9bS,11aS)-1-{[Bis-(4-chloro-phenyl)-methyl]-carbamoyl}-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,7,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridine-5-carboxylic acid tert-butyl ester(1026361-55-6)
• EPA Substance Registry System: (1S,3aS,3bS,9aR,9bS,11aS)-1-{[Bis-(4-chloro-phenyl)-methyl]-carbamoyl}-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,7,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridine-5-carboxylic acid tert-butyl ester(1026361-55-6)

Safety Data

• Hazardous Substances Data: 1026361-55-6(Hazardous Substances Data)

Upstream product

• 1026345-58-3 (1S,3aS,3bS,7S,9aR,9bS,11aS)-9a,11a-Dimethyl-7-triisopropylsilanyloxy-1,2,3,3a,3b,4,7,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridine-1,5-dicarboxylic acid 5-tert-butyl ester 1-methyl ester 
• 151520-57-9 (1S,3aS,4S,5S,7aS)-4-Carboxymethyl-7a-methyl-5-((1R,4S)-1-methyl-2-oxo-4-triisopropylsilanyloxy-cyclohexyl)-octahydro-indene-1-carboxylic acid methyl ester 
• 160001-82-1 (1S,3aS,4S,5S,7aS)-4-Chlorocarbonylmethyl-7a-methyl-5-((1R,4S)-1-methyl-2-oxo-4-triisopropylsilanyloxy-cyclohexyl)-octahydro-indene-1-carboxylic acid methyl ester 
• 151520-56-8 (1S,3aS,4S,5S,7aS)-7a-Methyl-5-((1R,4S)-1-methyl-2-oxo-4-triisopropylsilanyloxy-cyclohexyl)-4-(2-oxo-ethyl)-octahydro-indene-1-carboxylic acid methyl ester 
• 151520-59-1 17β-carbomethoxy-6-t-butoxycarbonyl-6-azaandrost-4-en-3-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 151520-60-4 17β-carboxy-6-(tert-butylcarboxy)-6-azaandrost-4-en-3-one 
• 14212-38-5 bis(4-chlorophenyl)methanamine 
• 151520-69-3 (1S,3aS,3bS,9aR,9bS,11aS)-1-Chlorocarbonyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,7,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridine-5-carboxylic acid tert-butyl ester 
• 1026526-05-5 (1S,3aS,3bS,7S,9aR,9bS,11aS)-7-Hydroxy-9a,11a-dimethyl-1,2,3,3a,3b,4,7,8,9,9a,9b,10,11,11a-tetradecahydro-cyclopenta[i]phenanthridine-1,5-dicarboxylic acid 5-tert-butyl ester 1-methyl ester 
• 151520-58-0 17β-Carbomethoxy-3β-triisopropylsilyloxy-6-azaandrost-5-ene 

Relevant articles and documents

6-Azasteroids: Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5α-Reductase and Human Adrenal 3β-Hydroxy-Δ5-steroid Dehydrogenase/3-Keto-Δ5-steroid Isomerase

6-Azaandrost-4-en-3-ones were synthesized and tested versus human type 1 and 2 steroid 5α-reductase (5AR) and human adrenal 3β-hydroxy-Δ5-steroid dehydrogenase/3-keto-Δ5-steroid isomerase (3BHSD) to explore the structure-activity rel