102734-34-9Relevant articles and documents
Transition-Metal-Free Esterification of Amides via Selective N-C Cleavage under Mild Conditions
Li, Guangchen,Lei, Peng,Szostak, Michal
, p. 5622 - 5625 (2018)
A general, transition-metal-free, and operationally simple method for esterification of amides by a highly selective cleavage of N-C(O) bonds under exceedingly mild conditions is reported. The reaction is characterized by broad substrate scope and excellent functional group tolerance. The potential of this mild esterification is highlighted by late-stage diversification of natural products and pharmaceuticals. Conceptually, the metal-free acyl functionalization of amides represents a significant step forward as a practical alternative to ligand exchange in acylmetal intermediates.
Ligand-free, palladium-catalyzed dihydrogen generation from TMDS: Dehalogenation of aryl halides on water
Bhattacharjya, Anish,Klumphu, Piyatida,Lipshutz, Bruce H.
supporting information, p. 1122 - 1125 (2015/03/14)
A mild and environmentally attractive dehalogenation of functionalized aryl halides has been developed using nanoparticles formed from PdCl2 in the presence of tetramethyldisiloxane (TMDS) on water. The active catalyst and reaction medium can be recycled. This method can also be applied to cascade reactions in a one-pot sequence.
