1027718-35-9Relevant articles and documents
A Convenient Synthetic Route to N-Aryl and N-Alkylamino(alkyl) Phosphonates and Phosphine Oxides
Couture, A.,Deniau, E.,Woisel, P.,Grandclaudon, P.
, p. 2483 - 2486 (1995)
A variety of phosphorylated N-aryl and N-alkyl N-formyl and N-tert-butoxycarbonylaminomethyl derivatives have been efficiently prepared by treatment of the corresponding chloromethyl derivatives with a trialkyl phosphite or an alkyl diphenylphosphinite.These bifunctional compounds may be deprotonated with LDA and further submitted to electrophilic substitution.An acidic treatment of the resulting compounds gives rise to a range of N-aryl and N-alkylamino(alkyl) phosphonates and phosphine oxides.