1027887-38-2

Basic information

• Product Name: N-(4-Fluoro-benzyl)-N-methyl-2-(4-nitro-phenoxy)-acetamide
• Synonyms: N-(4-Fluoro-benzyl)-N-methyl-2-(4-nitro-phenoxy)-acetamide
• CAS NO: 1027887-38-2
• Molecular Weight: 318.305
• Mol File: 1027887-38-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-Fluoro-benzyl)-N-methyl-2-(4-nitro-phenoxy)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Fluoro-benzyl)-N-methyl-2-(4-nitro-phenoxy)-acetamide(1027887-38-2)
• EPA Substance Registry System: N-(4-Fluoro-benzyl)-N-methyl-2-(4-nitro-phenoxy)-acetamide(1027887-38-2)

Safety Data

• Hazardous Substances Data: 1027887-38-2(Hazardous Substances Data)

Upstream product

• 19076-89-2 ethyl 4-nitrophenoxyacetate 
• 1798-11-4 4-nitrophenoxyacetic acid 
• 100-02-7 4-nitro-phenol 
• 20142-88-5 2-(4-nitrophenoxy)acetyl chloride 
• 405-66-3 (4-Fluoro-benzyl)-methyl-amine 

Downstream Products

• 163981-83-7 4-{2-[(4-Fluoro-benzyl)-methyl-amino]-ethoxy}-phenylamine 
• 1026748-84-4 2-(4-Amino-phenoxy)-N-(4-fluoro-benzyl)-N-methyl-acetamide 

Relevant articles and documents

Synthesis and Activity against Multidrug Resistance in Chinese Hamster Ovary Cells of New Acridone-4-carboxamides

A number of tricyclic carboxamides have been synthesized and tested to evaluate their ability to reverse multidrug resistance in the CHRC/5 cell line.Among them the acridone derivatives were the most potent.A key feature is the presence of a dimethoxybenzyl or phenethylamine cationic site, separated from the tricyclic lipophilic part by a carbamoylphenyl chain.Optimization led to compounds 2 orders of magnitude more active than the prototype inhibitors verapamil and amiodarone.On the basis of in vitro and in vivo activities, 9,10-dihydro-5-methoxy-9-oxo-N-phenyl>-4-acridinecarboxamide (84) has been selected for further development.