1029431-48-8 Usage
Description
(R)-1-(4-bromophenyl)-2-chloroethanol is a chiral chemical compound with the molecular formula C8H8BrClO. It is a white solid at room temperature and is soluble in organic solvents. (R)-1-(4-bromophenyl)-2-chloroethanol is known for its non-superimposable mirror image, which makes it a valuable building block in the synthesis of various pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
(R)-1-(4-bromophenyl)-2-chloroethanol is used as a building block for the synthesis of various pharmaceuticals. Its chiral nature allows for the creation of specific drug molecules that can interact differently with biological targets, leading to more effective treatments.
Used in Agrochemical Industry:
In the agrochemical industry, (R)-1-(4-bromophenyl)-2-chloroethanol is used as a starting material for the development of new compounds with pesticidal or herbicidal properties. Its unique structure contributes to the design of more targeted and effective agrochemicals.
Used as a Reagent in Chemical Synthesis:
(R)-1-(4-bromophenyl)-2-chloroethanol is also utilized as a reagent in the manufacturing of chiral pharmaceuticals. Its presence in the synthesis process can help create the desired enantiomer of a drug, which is crucial for ensuring the drug's efficacy and safety.
Used as an Intermediate in Chemical Production:
(R)-1-(4-bromophenyl)-2-chloroethanol serves as an intermediate in the production of other chemical compounds. Its versatility in chemical reactions makes it a valuable component in the synthesis of a wide range of products.
Safety Precautions:
It is important to handle (R)-1-(4-bromophenyl)-2-chloroethanol with care, as it may cause irritation to the skin, eyes, and respiratory system if proper precautions are not taken. Appropriate safety measures, such as wearing protective gear and working in a well-ventilated area, should be followed to minimize potential health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 1029431-48-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,9,4,3 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1029431-48:
(9*1)+(8*0)+(7*2)+(6*9)+(5*4)+(4*3)+(3*1)+(2*4)+(1*8)=128
128 % 10 = 8
So 1029431-48-8 is a valid CAS Registry Number.
1029431-48-8Relevant articles and documents
Unmasking the Hidden Carbonyl Group Using Gold(I) Catalysts and Alcohol Dehydrogenases: Design of a Thermodynamically-Driven Cascade toward Optically Active Halohydrins
Escot, Lorena,González-Granda, Sergio,Gotor-Fernández, Vicente,Lavandera, Iván
, p. 2552 - 2560 (2022/02/16)
A concurrent cascade combining the use of a gold(I) N-heterocyclic carbene (NHC) and an alcohol dehydrogenase (ADH) is disclosed for the synthesis of highly valuable enantiopure halohydrins in an aqueous medium and under mild reaction conditions. The meth
A novel C3-symmetric prolinol-squaramide catalyst for the asymmetric reduction of ketones by borane
Wu, Xiang-Fei,Min, Chang,Nyamzundui, Enkhtsetseg,Zhou, Hai-Bing,Dong, Chune
experimental part, p. 1640 - 1643 (2011/12/22)
A novel C3-symmetric prolinol-squaramide has been developed for the asymmetric reduction of ketones by borane. By using only 5 mol % catalyst 1a for the reaction, high yields and excellent enantioselectivities (up to 95% yield, 93% ee) were obtained. Moreover, 1a can be easily recovered by simple precipitation and re-used for four cycles without losing the selectivity. Copyright
Solid Forms Comprising A Cyclopropyl Amide Derivative
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Page/Page column 16, (2011/09/14)
This disclosure relates to at least one solid form of 4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide. This disclosure also relates to at least one pharmaceutical composition comprising at least one solid form described herein, methods of using the solid forms and pharmaceutical compositions comprised thereof, and processes of manufacturing the solid forms.
