1031417-77-2

Basic information

• Product Name: 1-Methylindazole-6-carboxylic acid
• Synonyms: 1-Methylindazole-6-carboxylic acid;1-Methyl-1H-indazol-6-carboxylic acid;1H-Indazole-6-carboxylic acid, 1-methyl-
• CAS NO: 1031417-77-2
• Molecular Formula: C9H8N2O2
• Molecular Weight: 176.17202
• Mol File: 1031417-77-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 383.7±15.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• PKA: 4.10±0.30(Predicted)
• CAS DataBase Reference: 1-Methylindazole-6-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methylindazole-6-carboxylic acid(1031417-77-2)
• EPA Substance Registry System: 1-Methylindazole-6-carboxylic acid(1031417-77-2)

Safety Data

• Hazardous Substances Data: 1031417-77-2(Hazardous Substances Data)

Usage

General Description

1-Methylindazole-6-carboxylic acid is a chemical compound that belongs to the class of organic compounds known as indazoles, which are aromatic heterocyclic compounds containing a benzene fused to an azole ring. The chemical formula of 1-Methylindazole-6-carboxylic acid is C9H8N2O2. It is defined as a monocarboxylic acid in which the carboxy group is attached to the sixth carbon of an indazole ring. Being a part of aromatic heterocyclic compounds, it features a system of alternating single and double bonds, which makes it relatively stable compared to other chemical compounds.

Upstream product

• 1007219-73-9 1-methyl-1H-indazole-6-carboxylic acid methyl ester 
• 74-88-4 methyl iodide 
• 170487-40-8 1H-indazole-6-carboxylic acid methyl ester 
• 57848-46-1 4-bromo-2-fluorobenzaldehyde 

Relevant articles and documents

Synthetic method 1 - methyl - 111H-indazole -6 - formic acid (by machine translation)

The invention provides a synthetic method, 1 - methyl - 111H-indazole -6 - formic acid. The synthesis method comprises 2 - fluorine -4 - bromobenzaldehyde and methylhydrazine as a raw material, and after the cyclization reaction is carried out 6 - bromo -1 - methyl indazole, then formate esterification reaction and hydrolysis reaction, and the 1 - methyl - 111H (indazole -6 - formic acid; isomers, and the like 1 are avoided, and the problem that impurities are difficult to remove in follow-up separation is avoided. Not only is the product purity, the yield of ring-forming 85% reaction can also reach the unitunits ?, the yield is higher, the product is suitable for small-scale preparation in laboratories, production, reaction conditions are easy to operate, control, production cost, and large-scale industrial production are facilitated. (by machine translation)

SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS

The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating mammals suffering from the condition of being overweight.