1032189-97-1

Basic information

• Product Name: 3,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl diethylcarbamate
• Synonyms: 3,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl diethylcarbamate
• CAS NO: 1032189-97-1
• Molecular Weight: 379.261
• Mol File: 1032189-97-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl diethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl diethylcarbamate(1032189-97-1)
• EPA Substance Registry System: 3,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl diethylcarbamate(1032189-97-1)

Safety Data

• Hazardous Substances Data: 1032189-97-1(Hazardous Substances Data)

Upstream product

• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 1135822-19-3 2-(diethylcarbamoyloxy)-3,5-dimethoxyphenylboronic acid 
• 1025324-83-7 3,5-dimethoxyphenyl diethylcarbamate 

Downstream Products

• 1032189-92-6 3,5-dimethoxy-2-(pyridin-4-yl)phenyl diethylcarbamate 
• 1448842-00-9 C₂₄H₃₆N₂O₄Si 

Relevant articles and documents

Combined directed metalation-suzuki-miyaura cross coupling strategies. Synthesis of isomeric chromenopyridinones and related annulated analogues

A general strategy encompassing a Directed ortho Metalation (DoM) - Suzuki-Miyaura cross coupling and Directed remote Metalation (DreM) sequence for the synthesis of 5H-chromeno[4,3-c]pyridin-5-ones 5a-j, 5H-chromeno[3,4-b] pyridin-5-ones 6a-j, 5H-chromeno[3,4-c]pyridin-5-ones 13a-d, 12H-benzo[7,8]chromenopyridin-12-ones 16a-c, 17a-c, and pyrido[3',4':4,5] pyrano[2,3-e]indazol-5(1H)-one analogues 18, 28 is reported. Thus, using the powerful directed metalation group properties of aryl O-carbamates 9a-h, 14a-c metalation-boronation followed by Suzuki-Miyaura coupling with 3-bromopyridine affords a variety of azabiaryls 7a-i, 8a-b, 12a-c, 15a-c which, upon DreM reaction leads to several series of chromenopyridinones 5a-j, 6a-j, 13a-d and pyridonaphthopyrones 16a-c, 17a-c. The synthesis of an unusual pyridopyranoindazolone 18 is also described.