103245-09-6Relevant articles and documents
AN EFFICIENT SYNTHESIS OF α-KETO AMIDES VIA REACTION OF α-(N-METHYLANILINO)-ACETONITRILE WITH ESTERS FOLLOWED BY HYDROLYSIS USING COPPER (II) ACETATE
Takahashi, Kazumasa,Shibasaki, Kenichiro,Ogura, Katsuyuki,Iida, Hirotada
, p. 859 - 862 (1983)
An efficient sequence proposed for the conversion of esters to α-keto amides involves the reaction of α-(N-methylanilino)-acetonitrile with esters to afford β0hydroxy-α-cyanoenamines of which hydrolysis using copper (II) acetate gives the corresponding α-keto amides in good yields.