103292-07-5

Basic information

• Product Name: 2,3,5-Tri-O-acetyl-6-O-trityl-D-galactono-1,4-lactone
• CAS NO: 103292-07-5
• Molecular Weight: 546.574
• Mol File: 103292-07-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3,5-Tri-O-acetyl-6-O-trityl-D-galactono-1,4-lactone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5-Tri-O-acetyl-6-O-trityl-D-galactono-1,4-lactone(103292-07-5)
• EPA Substance Registry System: 2,3,5-Tri-O-acetyl-6-O-trityl-D-galactono-1,4-lactone(103292-07-5)

Safety Data

• Hazardous Substances Data: 103292-07-5(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 76-83-5 trityl chloride 
• 2782-07-2 D-galactono-1,4-lactone 

Relevant articles and documents

SYNTHESIS OF 5-O-METHYL-D-GALACTOFURANOSE

5-O-Methyl-D-galactofuranose (7) was synthesized, for the first time, in five steps from D-galactono-1,4-lactone (1) in good overall yield.Tritylation and further acetylation of 1 gave 2,3,5-tri-O-acetyl-6-O-trityl-D-galactono-1,4-lactone (2); prolonged acetylation caused elimination to form 2,5-di-O-acetyl-3-deoxy-6-O-trityl-D-threo-hex-2-enono-1,4-lactone.Detritylation of 2 with BF3.Et2O occurred with acetyl migration and afforded 2,3,6-tri-O-acetyl-D-galactono-1,4-lactone (4).Methylation of 4 with CH2N2-BF3.Et2O gave 5-O-methyl-2,3,6-tri-O-acetyl-D-galactono-1,4-lactone.Subsequent reduction by disiamylborane followed by controlled deacetylation gave crystalline 7.The (1)H- and (13)C-n.m.r. spectra of 7 indicated a 1:1.3 ratio of the α and β furanose anomers.