2782-07-2 Usage
Description
D-GALACTONO-1,4-LACTONE, also known as a galactonolactone derived from D-galactonic acid, is a naturally occurring compound that plays a significant role in carbohydrate research. It is characterized by its unique chemical structure and properties, which make it a valuable component in various applications.
Uses
Used in Carbohydrate Research:
D-GALACTONO-1,4-LACTONE is used as an elution compound for the purification process of exo-β-D-galactofuranosidase enzyme. This application is crucial in the field of carbohydrate research, as it aids in the isolation and characterization of enzymes that are essential for understanding the biochemistry and biological functions of carbohydrates.
Purification Methods
Crystallise the lactone from EtOH, aqueous EtOH, MeOH or EtOAc. It is also purified by passage through a column of Amberlite IR-120 (H+ form), and the effluent and washings are then freeze-dried [Wolfrom & Thompson Methods in Carbohydrate Chemistry I 67 1963, Academic Press]. The 5,6-O-isopropylidene-D-galactono-1,4-lactone is purified by chromatography (EtOAc) and has m 165-167o (from EtOH/hexane), and 167.5-168.5o (from Me2CO/*C6H6) [NMR: Copel & Stick Aust J Chem 31 1371 1978.] [Beilstein 18 III/IV 3026, 18/5 V 18.]
Check Digit Verification of cas no
The CAS Registry Mumber 2782-07-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,8 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2782-07:
(6*2)+(5*7)+(4*8)+(3*2)+(2*0)+(1*7)=92
92 % 10 = 2
So 2782-07-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3-,4-,5+/m1/s1
2782-07-2Relevant articles and documents
Lien
, p. 1363,1364 (1959)
A simple synthesis of D-galactono-1,4-lactone and key building blocks for the preparation of galactofuranosides
De Talance, Vincent Lemau,Thiery, Emilie,Eppe, Guillaume,Bkassiny, Sandy El,Mortier, Jeremie,Vincent, Stephane P.
experimental part, p. 605 - 617 (2012/06/04)
The oxidation of D-galactose by Br2 to yield D-galactono-1,4-lactone was developed and applied to the preparation of key building blocks for the synthesis of galactofuranosides. Three D-galactono-1,4-lactone derivatives protected as acetates, TBDMS ether, or acetonide were directly obtained in two steps on multigram scale with only one purification step. A mild deacetylation methodology afforded pure D-galactono-1,4-lactone and a new reduction of the lactone functionality using K-selectride was also optimized.
A new efficient access to glycono-1,4-lactones by oxidation of unprotected itols by catalytic hydrogen transfer with RhH(PPh3)4-benzalacetone system
Isaac,Aizel,Stasik,Wadouachi,Beaupère
, p. 475 - 476 (2007/10/03)
Treatment of unprotected pentitols and hexitols with RhH(PPh3)4-benzalacetone system leads exclusively to glycono-1,4-lactones in 60-96% yield.