10355-06-3

Basic information

• Product Name: Benzene, 1-methyl-3-(methylsulfonyl)-
• CAS NO: 10355-06-3
• Molecular Formula: C8H10O2S
• Molecular Weight: 170.232
• Mol File: 10355-06-3.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-3-(methylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-3-(methylsulfonyl)-(10355-06-3)
• EPA Substance Registry System: Benzene, 1-methyl-3-(methylsulfonyl)-(10355-06-3)

Safety Data

• Hazardous Substances Data: 10355-06-3(Hazardous Substances Data)

Usage

General Description

Benzene, 1-methyl-3-(methylsulfonyl)- is a chemical compound with the molecular formula C8H10O2S. It belongs to the class of organic compounds known as toluenes, which are aromatic compounds containing a benzene moiety with a methyl group attached to it. This specific compound has an additional methylsulfonyl group attached to the benzene ring, which makes it a sulfone. It is commonly used as a solvent and in the production of other chemicals, such as pharmaceuticals and dyes. However, it is important to handle this chemical with caution, as it is considered harmful if inhaled, and it may cause skin and eye irritation upon contact.

Upstream product

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Downstream Products

• 5345-27-7 3-(methylsulfonyl)benzoic acid 
• 851785-28-9 methyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate 
• 253342-48-2 4,4,5,5-tetramethyl-2-m-tolyl-1,3,2-dioxaborolane 
• 1206713-19-0 (E/Z)-N'-[2-cyano-5-(3-methanesulphonylbenzyloxy)-4-bromophenyl]-N,N-dimethylformamidine 
• 82657-76-9 1-(bromomethyl)-3-(methylsulfonyl)benzene 
• 1206713-03-2 [6-bromo-7-(3-methanesulphonylbenzyloxy)quinazolin-4-yl](isopropyl)amine 
• 923001-98-3 1-(3-methylphenylsulfonyl)-5-hexen-2-one 
• 923001-90-5 (1R,5R)-1-(3-methylphenylsulfonyl)bicyclo[3.1.0]hexan-2-one 
• 923001-82-5 1-diazo-1-(3-methylphenylsulfonyl)-5-hexen-2-one 

Relevant articles and documents

Indium-catalysed aryl and alkyl sulfonylation of aromatics

Commercially available indium (III) triflate is shown to be an extremely efficient catalyst for the sulfonylation of both activated and deactivated aromatics.

Bismuth(III) trifluoromethanesulfonate: An efficient catalyst for the sulfonylation of arenes

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Friedel-Crafts sulfonylation of aromatics catalysed by solid acids: An eco-friendly route for sulfone synthesis

A mild and efficient catalytic method for Friedel-Crafts sulfonylation of arenes to the corresponding sulfones using a catalytic amount of reusable solid acid and arene- or alkanesulfonyl chlorides, sulfonic anhydrides and sulfonic acids as sulfonylating agents is described. Solid acids enable formation of a sulfone by the reaction of a sulfonic acid and an arene for the first time. In pursuit of the development of the best catalytic system, various metal-exchanged K10 montmorillonites and synthetic zeolites such as zeolite beta, zeolite Y and ZSM-5 have been screened for Friedel-Crafts sulfone synthesis. Fe3+-montmorillonite in the family of clays and zeolite beta in the family of zeolites exhibit higher activity. The activity is correlated to the presence of the right mix of Bronsted and Lewis acidic sites. The regioselective sulfonylation of toluene and naphthalene are studied in which para and beta selectivities are observed respectively. The Royal Society of Chemistry 2000.

Synergistic cooperative effect of CF3SO2Na and bis(2-butoxyethyl)ether towards selective oxygenation of sulfides with molecular oxygen under visible-light irradiation

A safe, practical and eco-friendly method for the switchable synthesis of sulfoxides and sulfones through visible-light-initiated oxygenation of sulfides at ambient temperature under transition-metal-, additives-free and minimal solvent conditions. The synergistic catalytic efforts between CF3SO2Na and 2-butoxyethyl ether represents the key promoting factor for the reaction. This journal is

Lifitegrast intermediate and preparation method thereof

The invention relates to the field of pharmaceutical and chemical production, and discloses a lifitegrast intermediate and a preparation method thereof. A reaction route of the preparation method is as described in the specification. The preparation metho