10381-71-2

Basic information

• Product Name: Benzene, 1-methyl-4-(2-propenylsulfinyl)-
• CAS NO: 10381-71-2
• Molecular Formula: C10H12OS
• Molecular Weight: 180.271
• Mol File: 10381-71-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-4-(2-propenylsulfinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-4-(2-propenylsulfinyl)-(10381-71-2)
• EPA Substance Registry System: Benzene, 1-methyl-4-(2-propenylsulfinyl)-(10381-71-2)

Safety Data

• Hazardous Substances Data: 10381-71-2(Hazardous Substances Data)

Usage

General Description

Benzene, 1-methyl-4-(2-propenylsulfinyl)-, commonly known as allicin, is a chemical compound found in garlic that is responsible for its distinctive odor and taste. It is a sulfurous compound with a strong and pungent scent. Allicin is formed when garlic is crushed or chopped, causing the enzyme alliinase to convert the odorless compound alliin into allicin. It has been studied for its potential health benefits, including antioxidant, antimicrobial, and anti-inflammatory properties. Allicin is also used as a flavoring agent in cooking and as a natural remedy for various ailments.

Upstream product

• 106-95-6 allyl bromide 
• 106-45-6 para-thiocresol 
• 672-78-6 methyl p-toluene sulfinate 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 723336-87-6 trimethylsilyl prop-2-ene-1-sulfinate 
• 911820-17-2 3-[(4-methylphenyl)sulfanyl]propanoic acid tert-butyl ester 
• 911820-09-2 3-[(4-methylphenyl)sulfinyl]propanoic acid tert-butyl ester 
• 591-87-7 Allyl acetate 
• 31536-19-3 allyl 4-methylbenzenesulfinate 
• 1516-28-5 allyl (p-tolyl)sulfide 
• 933-00-6 p-methylbenzenesulfenyl chloride 
• 107-18-6 allyl alcohol 

Downstream Products

• 110210-79-2 (E)-6-(4-methylphenyl)-sulphonyl-2-phenyl-5-hexene-3-ol 
• 87448-25-7 1-(p-nitrophenyl)-2-(p-methylbenzenesulfinyl)but-3-en-1-ol 
• 87448-32-6 1-(1-naphthyl)-2-(p-methylbenzenesulfinyl)but-3-en-1ol 
• 109795-94-0 (3aS,6aS)-5,5-Dimethyl-1-methylene-6a-[(E)-3-((R)-toluene-4-sulfinyl)-allyl]-hexahydro-pentalen-2-one 
• 119582-24-0 (1S,3aS,6aS)-1-(tert-Butyl-dimethyl-silanyloxymethyl)-5,5-dimethyl-6a-[(E)-3-((R)-toluene-4-sulfinyl)-allyl]-hexahydro-pentalen-2-one 
• 103867-69-2 (E)-2-Phenyl-6-(toluene-4-sulfinyl)-hex-5-en-3-ol 
• 103867-64-7 2-Phenyl-4-(toluene-4-sulfinyl)-hex-5-en-3-ol 
• 103867-73-8 (E)-5-cyclohexyl-2-hexene-1,4-diol 
• 103867-73-8 (E)-5-cyclohexyl-2-hexene-1,4-diol 
• 103867-68-1 (E)-2-Cyclohexyl-6-(toluene-4-sulfinyl)-hex-5-en-3-ol 
• 103867-63-6 2-Cyclohexyl-4-(toluene-4-sulfinyl)-hex-5-en-3-ol 
• 103867-67-0 (E)-5,6-Dimethyl-1-(toluene-4-sulfinyl)-hept-1-en-4-ol 
• 103867-62-5 5,6-Dimethyl-3-(toluene-4-sulfinyl)-hept-1-en-4-ol 

Relevant articles and documents

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Aryne 1,2,3,5-Tetrasubstitution Enabled by 3-Silylaryne and Allyl Sulfoxide via an Aromatic 1,3-Silyl Migration

Although benzyne has been well-known to serve as a synthon that can conveniently prepare various 1,2-difunctionalized benzenes, the sites other than its formal triple bond remain silent in typical benzyne transformations. An unprecedented aryne 1,2,3,5-tetrasubstitution was realized from 3-silylbenzyne and aryl allyl sulfoxide, the mechanistic pathway of which includes a regioselective aryne insertion into the SO bond, a [3,6]-sigmatropic rearrangement, and a thermal aromatic 1,3-silyl migration cascade.

1,2,3,5-tetrasubstituted benzene containing 5-silicon groups and synthesis method thereof

The invention discloses a 1,2,3,5-tetrasubstituted benzene containing 5-silicon groups and a synthesis method thereof. The tetrasubstituted benzene has a structure as shown in. A. The method of synthesis of the tetrasubstituted benzene includes synthesis

One-Pot Sulfoxide Synthesis Exploiting a Sulfinyl-Dication Equivalent Generated from a DABSO/Trimethylsilyl Chloride Sequence

A one-pot process for the synthesis of unsymmetrical sulfoxides using organometallic nucleophiles is described. Sulfur dioxide, delivered from the surrogate DABSO (DABCO-bis(sulfur dioxide)), acts as the initial electrophile and combines with the first organometallic reagent to generate a sulfinate intermediate. In situ conversion of the sulfinate to a sulfinate silyl ester, using TMS-Cl (trimethylsilyl chloride), generates a second electrophile, allowing addition of a second organometallic reagent. Organolithium or Grignard reagents can be employed, delivering sulfoxides in good to excellent yields.