10412-98-3 Usage
Description
5-KETOHEXANENITRILE, also known as 5-oxohexanonitrile, is an organic compound that serves as a versatile reagent in various chemical reactions. It is characterized by its ability to undergo electroreduction, leading to the formation of the corresponding intermolecularly coupled product.
Uses
Used in Chemical Synthesis:
5-KETOHEXANENITRILE is used as a reagent for [facilitating a wide range of chemical reactions] because of its [electroreduction property and ability to form intermolecularly coupled products].
Used in Pharmaceutical Industry:
5-KETOHEXANENITRILE is used as an intermediate in the synthesis of [various pharmaceutical compounds] due to its [reactivity and potential for creating diverse molecular structures].
Used in Research and Development:
5-KETOHEXANENITRILE is used as a research compound for [exploring new chemical reactions and understanding reaction mechanisms] as it [exhibits unique electrochemical properties].
Used in Material Science:
5-KETOHEXANENITRILE is used as a building block in the development of [novel materials with specific properties], taking advantage of its [reactivity and potential for creating complex structures].
Used in Environmental Applications:
5-KETOHEXANENITRILE is used as a component in [environmental remediation processes], where its [chemical reactivity can be harnessed to neutralize or transform harmful substances].
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 2594, 1950 DOI: 10.1021/ja01162a068
Check Digit Verification of cas no
The CAS Registry Mumber 10412-98-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,1 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10412-98:
(7*1)+(6*0)+(5*4)+(4*1)+(3*2)+(2*9)+(1*8)=63
63 % 10 = 3
So 10412-98-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H9NO/c1-6(8)4-2-3-5-7/h2-4H2,1H3
10412-98-3Relevant articles and documents
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Meltzer et al.
, p. 712,713 (1960)
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Ag+-CATALYZED OXIDATION OF ALKANONE CYANOHYDRINS BY PEROXYDISULFATE IONS: GENERATION AND REACTIONS OF 1-CYANOALKOXYL RADICALS
Ogibin, Yu. N.,Velibekova, D. S.,Katsin, M. I.,Troyanskii, E. I.,Nikishin, G. I.
, p. 127 - 133 (1981)
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Baumgarten,Eifert
, p. 3015 (1953)
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Oxidation of Secondary Methyl Ethers to Ketones
Gilissen, Pieter J.,Blanco-Ania, Daniel,Rutjes, Floris P. J. T.
, p. 6671 - 6679 (2017/07/15)
We present a mild way of converting secondary methyl ethers into ketones using calcium hypochlorite in aqueous acetonitrile with acetic acid as activator. The reaction is compatible with various oxygen- and nitrogen-containing functional groups and afforded the corresponding ketones in up to 98% yield. The use of this methodology could expand the application of the methyl group as a useful protecting group.
Photoinduced direct cyanation of C(sp3)-H bonds
Hoshikawa, Tamaki,Yoshioka, Shun,Kamijo, Shin,Inoue, Masayuki
, p. 874 - 887 (2013/05/09)
A general and practical synthetic protocol for the direct transformation of unreactive C(sp3)-H bonds to C(sp3)-CN bonds has been developed. The homolytic cleavage of the C-H bond is initiated by photo-excited benzophenone, and the resulting carbon radical subsequently reacts with tosyl cyanide to afford the corresponding nitrile in a highly efficient manner. The present methodology is widely applicable to various starting materials including ethers, alcohols, amine derivatives, alkanes, and alkylbenzenes. This newly developed C-H cyanation protocol provides a powerful tool for selective one-carbon elongation for the construction of architecturally complex molecules. Georg Thieme Verlag Stuttgart - New York.