104167-26-2

Basic information

• Product Name: Phosphonic acid, [(2-aminophenyl)methyl]-, diethyl ester
• CAS NO: 104167-26-2
• Molecular Formula: C11H18NO3P
• Molecular Weight: 243.243
• Mol File: 104167-26-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [(2-aminophenyl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [(2-aminophenyl)methyl]-, diethyl ester(104167-26-2)
• EPA Substance Registry System: Phosphonic acid, [(2-aminophenyl)methyl]-, diethyl ester(104167-26-2)

Safety Data

• Hazardous Substances Data: 104167-26-2(Hazardous Substances Data)

Upstream product

• 104894-25-9 C₁₅H₂₂NO₅P 
• 88-72-2 1-methyl-2-nitrobenzene 
• 2464-33-7 N-(2-methylphenyl)phthalimide 
• 57365-06-7 2-<2-(bromomethyl)phenyl>-1H-isoindole-1,3(2H)-dione 
• 552-89-6 2-nitro-benzaldehyde 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 79202-15-6 diethyl (hydroxy)(2-nitrophenyl)methylphosphonate 
• 140150-99-8 diethyl <<2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl>methyl>phosphonate 
• 4914-12-9 diethyl 2-nitrobenzylphosphonate 

Downstream Products

• 1158382-83-2 diethyl 2-(n-pentylsulfonamido)benzylphosphonate 
• 1158382-86-5 diethyl 2-(n-nontylsulfonamido)benzylphosphonate 

Relevant articles and documents

Poly(o-aminobenzylphosphonic acid): a Novel Water Soluble, Self-doped Functionalized Polyaniline

A novel self-doped polymer having alkylphosphonic acid moieties on polyaniline is synthesized from persulfate oxidative coupling of o-aminobenzylphosphonic acid 3; the resulting polymer, apart from being water soluble in its self-doped monosodium salt for

Discovery and characterization of aryl isonitriles as a new class of compounds versus methicillin- and vancomycin-resistant Staphylococcus aureus

Methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) have emerged as a global health concern. A new class of compounds featuring an aryl isonitrile moiety has been discovered that exhibits potent inhibitory activity against several clinically-relevant MRSA and VRSA isolates. Structure-activity relationship studies have been conducted to identify the aryl isonitrile group as the key functional group responsible for the observed antibacterial activity. The most potent antibacterial aryl isonitrile analogs (MIC 2 μM) did not show any toxicity against mammalian cells up to a concentration of 64 μM.

NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, METHODS OF USE FOR SAME, AND METHODS FOR PREPARING SAME

The present invention relates to a novel class of compounds comprising formula I, wherein n is 0 or 1. A is NR1, O, or S, wherein R1 is H, hydroxyl, C1-C10 alkyl, C1-C10 alkoxy, alkenyl, aryl, alkylaryl or arylalkyl. X is a carboxylate, a phosphonate, or a phosphate residue, or a C1-C10 alkyl residue optionally substituted with a carboxylate, phosphonate or phosphate residue. Y is a C1-C20 alkyl, alkenyl, halide, hydroxyl, C1-C20 alkoxy, aryl, alkylaryl, arylalkyl, cycloalkyl, cycloalkenyl, or a heterocyclic ring and is optionally substituted with one or more halides. Z is a H, a hydroxyl group, a halide, an aryl group, an alkylaryl group, an arylalkyl group, a cycloalkyl group, a cycloalkenyl group or a heterocyclic ring and is optionally substituted with one or more C1-C10 alkyl groups, C1-C10alkoxy groups, hydroxyl groups, cyano groups, carboxylate groups, halides, aryl groups, alkylaryl groups, arylalkyl groups, cycloalkyl groups, cycloalkenyl groups or heterocyclic rings.

AMIDES AS SPHINGOMYELINE INHIBITORS

The present invention, relates to compounds of formula (I), wherein A is hydrogen or (C1-4)alkyl, R1 is a group Y-R2, Y is not present or is (C1-4)alkylene, which alkylene optionally is substituted, e.g. one or