104366-22-5

Basic information

• Product Name: 3-Thiophenecarbonitrile, 2-amino-4-methoxy-
• Synonyms: 3-Thiophenecarbonitrile, 2-amino-4-methoxy-;2-Amino-4-methoxythiophene-3-carbonitrile
• CAS NO: 104366-22-5
• Molecular Formula: C6H6N2OS
• Molecular Weight: 154.19
• Mol File: 104366-22-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Thiophenecarbonitrile, 2-amino-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenecarbonitrile, 2-amino-4-methoxy-(104366-22-5)
• EPA Substance Registry System: 3-Thiophenecarbonitrile, 2-amino-4-methoxy-(104366-22-5)

Safety Data

• Hazardous Substances Data: 104366-22-5(Hazardous Substances Data)

Upstream product

• 5515-16-2 2-(methoxyethylidene)propanedinitrile 
• 67-56-1 methanol 
• 1445-45-0 Trimethyl orthoacetate 
• 109-77-3 malononitrile 

Relevant articles and documents

Basic Ionic Liquid [bmIm]OH-Mediated Gewald Reaction as Green Protocol for the Synthesis of 2-Aminothiophenes

A simple, efficient, and environmental friendly procedure was developed based on the Gewald reaction for the synthesis of 2-aminothiophenes using a basic ionic liquid [bmIm]OH as both catalyst and solvent. Besides being a green protocol, the method offers advantages of successful synthesis of a variety of alkyl, aryl, alkoxy, and alkylamino-2-aminothiophenes in good yields.