1047630-52-3 Usage
Description
2-Thiophenecarboxylic acid, 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-, methyl ester is a chemical compound that features a thiophene ring with a carboxylic acid group, a chlorine atom, and a methyl ester group attached to it. 2-Thiophenecarboxylic acid, 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-, methyl ester is known for its potential biological activity and has been studied for its anti-inflammatory and antifungal properties. It is also being investigated for its potential use in treating various diseases and conditions.
Used in Pharmaceutical Industry:
2-Thiophenecarboxylic acid, 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-, methyl ester is used as an intermediate in the synthesis of various drugs and pharmaceutical compounds. Its unique structure and properties make it a valuable component in the development of new medications.
Used in Anti-inflammatory Applications:
2-Thiophenecarboxylic acid, 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-, methyl ester is being studied for its potential anti-inflammatory properties, which could make it useful in the treatment of conditions characterized by inflammation, such as arthritis or other inflammatory disorders.
Used in Antifungal Applications:
2-Thiophenecarboxylic acid, 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-, methyl ester has also been investigated for its antifungal properties, indicating its potential use in treating fungal infections.
Used in Disease and Condition Treatment:
2-Thiophenecarboxylic acid, 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-, methyl ester is being explored for its potential use in the treatment of various diseases and conditions, although further research is needed to determine its full therapeutic potential and safety.
It is important to handle 2-Thiophenecarboxylic acid, 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)-, methyl ester with care, as it may pose certain health and safety risks if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 1047630-52-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,7,6,3 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1047630-52:
(9*1)+(8*0)+(7*4)+(6*7)+(5*6)+(4*3)+(3*0)+(2*5)+(1*2)=133
133 % 10 = 3
So 1047630-52-3 is a valid CAS Registry Number.
1047630-52-3Relevant articles and documents
AFURESERTIB: Protein kinase B (PKB) inhibitor Oncolytic
Conkel,Benson
, p. 541 - 546 (2014/12/11)
The phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway plays key roles in cellular proliferation and survival. Mutations and alterations in this signal transduction pathway have been described in a variety of solid and hematopoietic malignancies, which may contribute to perpetuation of the disease in a number of ways. Increasing interest in targeting particular facets of this signaling cascade has led to the development of a number of novel anticancer agents, including afuresertib (GSK-2110183), an orally bioavailable pan-inhibitor of the RAC-alpha serine/threonine protein kinase, also referred to as protein kinase B or proto-oncogene c-Akt. The present review summarizes the preclinical and pharmacological aspects of afuresertib and early clinical experience.