1047976-80-6

Basic information

• Product Name: C₃₄H₃₅N₃O₁₅
• Synonyms: C₃₄H₃₅N₃O₁₅
• CAS NO: 1047976-80-6
• Molecular Weight: 725.663
• Mol File: 1047976-80-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₄H₃₅N₃O₁₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₃₅N₃O₁₅(1047976-80-6)
• EPA Substance Registry System: C₃₄H₃₅N₃O₁₅(1047976-80-6)

Safety Data

• Hazardous Substances Data: 1047976-80-6(Hazardous Substances Data)

Upstream product

• 1047976-79-3 C₃₅H₃₇N₃O₁₅ 

Downstream Products

• 127810-79-1 8-benzyl DC-81 

Relevant articles and documents

Pyrrolo[2,1-c][1,4]benzodiazepine-β-glucuronide prodrugs with a potential for selective therapy of solid tumors by PMT and ADEPT strategies

Pyrrolo[2,1-c][1,4]benzodiazepine-β-glucuronide prodrugs 15a-b, with a potential for selective therapy of solid tumors by PMT and ADEPT have been designed, synthesized and evaluated for selective cytotoxicity in the presence of the enzyme β-glucuronidase. The prodrugs have been found to possess reduced cytotoxicity compared to the parent moieties, and are excellent substrates for the enzyme, exhibiting cytotoxicity selectively in the presence of the enzyme. Enhanced water solubility and improved stability are the other important outcomes upon modifying these molecules as their prodrugs.