1048380-54-6

Basic information

• Product Name: (R)-1-(4-chlorophenyl)-2-[(2-hydroxyethyl)(phenyl)amino]-1-ethanol
• Synonyms: (R)-1-(4-chlorophenyl)-2-[(2-hydroxyethyl)(phenyl)amino]-1-ethanol
• CAS NO: 1048380-54-6
• Molecular Weight: 291.777
• Mol File: 1048380-54-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(4-chlorophenyl)-2-[(2-hydroxyethyl)(phenyl)amino]-1-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(4-chlorophenyl)-2-[(2-hydroxyethyl)(phenyl)amino]-1-ethanol(1048380-54-6)
• EPA Substance Registry System: (R)-1-(4-chlorophenyl)-2-[(2-hydroxyethyl)(phenyl)amino]-1-ethanol(1048380-54-6)

Safety Data

• Hazardous Substances Data: 1048380-54-6(Hazardous Substances Data)

Upstream product

• 2788-86-5 (R)-2-(4-chlorophenyl)oxirane 
• 122-98-5 2-Anilinoethanol 

Downstream Products

• 1048380-42-2 (R)-2-(4-chlorophenyl)-4-phenyl-1-(2-propenyl)hexahydropyrazine 

Relevant articles and documents

METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE

The objective of the present invention is to produce an optically active 2-arylpiperazine derivative useful as a synthetic intermediate for pharmaceutical products and agricultural chemicals from inexpensive and readily available starting material by an industrially practicable method. The objective can be accomplished by treating an optically active substituted aminodiol derivative produced from an optically active styrene oxide derivative with a sulfonating agent in the presence of a base, and then reacting an amine compound to obtain the 2-arylpiperazine derivative. Especially, an optically active 1-unsubstituted-2-arylpiperazine derivative can be produced by treating an optically active 1-allyl-2-arylpiperazine derivative with water in the presence of a transition metal catalyst for deallylation.