105337-67-5

Basic information

• Product Name: Benzene, (3-ethoxy-1-butenyl)-
• CAS NO: 105337-67-5
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• Mol File: 105337-67-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzene, (3-ethoxy-1-butenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (3-ethoxy-1-butenyl)-(105337-67-5)
• EPA Substance Registry System: Benzene, (3-ethoxy-1-butenyl)-(105337-67-5)

Safety Data

• Hazardous Substances Data: 105337-67-5(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 52755-39-2 (2E)-1-phenylbut-2-en-1-ol 
• 16939-57-4 (E)-buta-1,3-dienylbenzene 
• 36004-04-3 ethyl (E)-1-phenylbut-1-en-3-ol 
• 60-29-7 diethyl ether 
• 621-82-9 Cinnamic acid 
• 100-42-5 styrene 
• 7107-13-3 Aethyl-<3-chlor-1-methyl-3-phenyl-propyl>-aether 
• 536-74-3 phenylacetylene 
• 6738-06-3 phenylethynylmagnesium bromide 
• 27975-64-0 (3-ethoxybut-1-yn-1-yl)benzene 
• 14371-10-9 (E)-3-phenylpropenal 
• 140-10-3 (E)-3-phenylacrylic acid 

Downstream Products

• 101266-90-4 (E)-(3-propoxybut-1-enyl)benzene 
• 24808-74-0 (E)-(3-methoxybut-1-en-1-yl)benzene 
• 82045-04-3 (rac)-(E)-2-acetoxy-4-phenylbut-3-ene 

Relevant articles and documents

Dimethylzinc-Initiated Radical Coupling of β-Bromostyrenes with Ethers and Amines

A new coupling reaction has been developed in which β-bromostyrenes react with ethers and tertiary amines to introduce the styryl group in the α-position. The transformation is mediated by Me2Zn/O2 with 10 % MnCl2 and is believed to proceed by a radical addition-elimination mechanism. The ether and the amine are employed as solvent and the coupling takes place through the most stable α radical for unsymmetrical substrates. The products are obtained in moderate to good yields as the pure E isomers. The coupling can be achieved with a range of smaller cyclic and acyclic ethers/amines as well as various substituted β-bromostyrenes.

C(sp3)–H bond functionalization of non-cyclic ethers by decarboxylative oxidative coupling with α,β-unsaturated carboxylic acids

A copper-catalyzed decarboxylative oxidative coupling of α,β-unsaturated carboxylic acids with non-cyclic ethers is developed. This method provides a new approach for C(sp3)–H bond functionalization of non-cyclic ethers. Mechanism study shows the reaction involves a radical process.

Hydrogen-bond-activated palladium-catalyzed allylic alkylation via allylic alkyl ethers: Challenging leaving groups

C-O bond cleavage of allylic alkyl ether was realized in a Pd-catalyzed hydrogen-bond-activated allylic alkylation using only alcohol solvents. This procedure does not require any additives and proceeds with high regioselectivity. The applicability of this transformation to a variety of functionalized allylic ether substrates was also investigated. Furthermore, this methodology can be easily extended to the asymmetric synthesis of enantiopure products (99% ee).