10548-84-2

Basic information

• Product Name: ethoxymethyl-4 dimethoxy-1,2 benzene
• Synonyms: ethoxymethyl-4 dimethoxy-1,2 benzene
• CAS NO: 10548-84-2
• Molecular Weight: 196.246
• Mol File: 10548-84-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethoxymethyl-4 dimethoxy-1,2 benzene(CAS DataBase Reference)
• NIST Chemistry Reference: ethoxymethyl-4 dimethoxy-1,2 benzene(10548-84-2)
• EPA Substance Registry System: ethoxymethyl-4 dimethoxy-1,2 benzene(10548-84-2)

Safety Data

• Hazardous Substances Data: 10548-84-2(Hazardous Substances Data)

Upstream product

• 75-03-6 ethyl iodide 
• 93-03-8 (3,4-dimethoxyphenyl)methanol 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 79411-60-2 l'α-chloro α-ethoxymethyltributyletain 
• 2246-26-6 1,2-dihydro-2-methylpapaverine 

Downstream Products

• 65051-46-9 veratrylmercapto-acetic acid 
• 54035-89-1 (3,4-dimethoxy-phenyl)-methanesulfonic acid 

Relevant articles and documents

Evidence for a Radical Chain Mechanism for the Knabe Reaction of 1,2-Dihydro-2-methylpapaverine

A free radical chain mechanism is proposed for the Knabe reaction and the accompanying elimination reaction on account of their nonintegral reaction order and of successful inhibition experiments. 3,4-Dimethoxybenzyl radicals are the chain carrying species.Battersby's synthesis of N-methylpavine (19) from 1,2-dihydro-2-methylpapaverine (9) is dependent on the presence of formic acid as radical chain inhibitor.In the presence of inhibitors 1-benzyl-1,4-dihydro-2-methylisoquinolinium ions like 10 are persistent species whose chemistry can now be investigated.

QUELQUES ASPECTS DE LA REACTIVITE DE L'α-CHLORO α-ETHOXYMETHYLTRIBUTYLETAIN: ETHERIFICATION REDUCTRICE DES ALDEHYDES AROMATIQUES ET MISE EN EVIDENCE DE FORMYLTRIBUTYLETAIN LORS DE LA REACTION D'HYDROLYSE

α-Chloro-α-ethoxymethyltributyltin reacts with aromatic aldehydes and leads to benzyl ethyl ethers with formation of tributyltin chloride and carbon monoxide.Analogously the formation of ethoxymethyltributyltin and tributyltyn chloride on hydrolysis of this new organometallic reagent is explained by a process involving formyltributyltin as an unstable intermediate.This explanation is supported by the observation of an electronic spectrum between 350 and 450 nm during the hydrolysis.