105872-07-9

Basic information

• Product Name: 2-(4-butylphenyl)acetonitrile
• Synonyms: 2-(4-butylphenyl)acetonitrile
• CAS NO: 105872-07-9
• Molecular Formula: C₁₂H₁₅N
• Molecular Weight: 173.25
• Mol File: 105872-07-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-butylphenyl)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-butylphenyl)acetonitrile(105872-07-9)
• EPA Substance Registry System: 2-(4-butylphenyl)acetonitrile(105872-07-9)

Safety Data

• Hazardous Substances Data: 105872-07-9(Hazardous Substances Data)

Usage

Classification

Aromatic nitrile

Common uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Medical applications

Production of pharmaceutical drugs for various medical treatments

Synthesis

Building block in the synthesis of other organic compounds

Industrial applications

Potential use in the development of new materials

Versatility

Range of uses in the pharmaceutical, agricultural, and industrial fields

Upstream product

• 36078-54-3 1-butyl-4-(chloromethyl)benzene 
• 151-50-8 potassium cyanide 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 63676-96-0 lithium tri-n-butylzincate 
• 199608-28-1 4-iodobenzyl methanesulfonate 
• 10531-16-5 p-butylbenzylbromide 
• 143-33-9 sodium cyanide 
• 28788-62-7 4-butylbenzoyl chloride 
• 1200-14-2 4-(n-butyl)benzaldehyde 
• 60834-63-1 p-butylbenzyl alcohol 
• 18282-51-4 4-iodo-benzyl alcohol 
• 7677-24-9 trimethylsilyl cyanide 
• 109-72-8 n-butyllithium 
• 16532-79-9 4-Bromophenylacetonitrile 

Downstream Products

• 14377-19-6 [4-(n-Butyl)phenyl]acetic acid 
• 743355-59-1 4-butyl-phenethylamine 
• 960048-18-4 2-(4-n-butylphenyl)-3-oxo-4-phenylbutanenitrile 
• 950508-68-6 2-(4-n-butylphenyl)-3-phenylpropan-2-one 
• 103167-96-0 (4-butyl-phenyl)-acetic acid dodecyl ester 

Relevant articles and documents

Synthesis of phenylenevinylene oligothiophene derivatives with and without cyano side substitution and evaluation of optoelectronic characteristics

Two types of phenylenevinylene terthiophene with and without cyano side substitution were synthesized to investigate the effect of the molecular structure on optoelectronic properties. The oligothiophene with cyano side substitution exhibited large bathoc

ALPHA,BETA UNSATURATED METHACRYLIC ESTERS WITH ANTI-INFLAMMATORY PROPERTIES

The invention relates to compounds of formula (I): wherein A, RA1, RA2, RB, RC and RD are as defined herein, and associated aspects.

Scalable Negishi Coupling between Organozinc Compounds and (Hetero)Aryl Bromides under Aerobic Conditions when using Bulk Water or Deep Eutectic Solvents with no Additional Ligands

Pd-catalyzed Negishi cross-coupling reactions between organozinc compounds and (hetero)aryl bromides have been reported when using bulk water as the reaction medium in the presence of NaCl or the biodegradable choline chloride/urea eutectic mixture. Both C(sp3)-C(sp2) and C(sp2)-C(sp2) couplings have been found to proceed smoothly, with high chemoselectivity, under mild conditions (room temperature or 60 °C) in air, and in competition with protonolysis. Additional benefits include very short reaction times (20 s), good to excellent yields (up to 98 %), wide substrate scope, and the tolerance of a variety of functional groups. The proposed novel protocol is scalable, and the practicability of the method is further highlighted by an easy recycling of both the catalyst and the eutectic mixture or water.